As x-ray and electron tomography is pushed further into the nanoscale, the limitations of rotation stages become more apparent, leading to challenges in the alignment of the acquired projection images. Here we present an approach for rapid post-acquisition alignment of these projections to obtain high quality three-dimensional images. Our approach is based on a joint estimation of alignment errors, and the object, using an iterative refinement procedure. With simulated data where we know the alignment error of each projection image, our approach shows a residual alignment error that is a factor of a thousand smaller, and it reaches the same error level in the reconstructed image in less than half the number of iterations. We then show its application to experimental data in x-ray and electron nanotomography.
Abstract-A number of computational imaging techniques have been introduced to improve image quality by increasing light throughput. These techniques use optical coding to measure a stronger signal level. However, the performance of these techniques is limited by the decoding step, which amplifies noise. While it is well understood that optical coding can increase performance at low light levels, little is known about the quantitative performance advantage of computational imaging in general settings. In this paper, we derive the performance bounds for various computational imaging techniques. We then discuss the implications of these bounds for several real-world scenarios (illumination conditions, scene properties and sensor noise characteristics). Our results show that computational imaging techniques do not provide a significant performance advantage when imaging with illumination brighter than typical daylight. These results can be readily used by practitioners to design the most suitable imaging systems given the application at hand.
In this work, we propose using camera arrays coupled with coherent illumination as an effective method of improving spatial resolution in long distance images by a factor of ten and beyond. Recent advances in ptychography have demonstrated that one can image beyond the diffraction limit of the objective lens in a microscope. We demonstrate a similar imaging system to image beyond the diffraction limit in long range imaging. We emulate a camera array with a single camera attached to an X-Y translation stage. We show that an appropriate phase retrieval based reconstruction algorithm can be used to effectively recover the lost high resolution details from the multiple low resolution acquired images. We analyze the effects of noise, required degree of image overlap, and the effect of increasing synthetic aperture size on the reconstructed image quality. We show that coherent camera arrays have the potential to greatly improve imaging performance. Our simulations show resolution gains of 10× and more are achievable. Furthermore, experimental results from our proof-of-concept systems show resolution gains of 4 × −7× for real scenes. Finally, we introduce and analyze in simulation a new strategy to capture macroscopic Fourier Ptychography images in a single snapshot, albeit using a camera array.
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