Aim: Covid-19, which emerged in China in the last days of 2019 has spread to the whole world primarily affecting health-care professionals who fight on the forefront against the outbreak. In this study, we aimed to determine depression prevalence among health-care professionals who represent the riskiest group for Covid-19 and its secondary problems. Material and Methods:The study is a cross-sectional study consisting of health-care staff working in emergency ambulance service of Bolu. A total of 226 subjects was included in the study. Results:The mean age of the subjects in the study was 31.50±7.19, the youngest participant was 20 and the oldest was 58 years old. 54.4% of the participants were male, 45.6% were female. Among the participants 11.9% had mild depression and 13.7% moderate depression. The rate of those who suffered from severe depression was found to be only 1.8%. Female gender and co-existing chronic diseases seemed to be risk factors for occurrence of depression. Conclusion:During the on-going Covid-19 outbreak, health-care workers seem to be one of the risk groups for depression as well as for infection.