The aim of the study was to develop SQUID-magnetometer system and to reveal the ability of above system to monitor the dynamics of injected magnetic nanoparticles (MNP) into rabbit's body. MNP were prepared by first precipitation of ferrous hydroxide which was then crystallized into magnetite in the presence of potassium nitrate as mild oxidizing agent and further the MNP surface was modified with oxidized hidroxyethylstarch. The dynamics of the MNP distribution into the rabbit tissues according to the electron-spin resonance (ESR) data shows that after 60 min of nanomaterial preparation circulation into the rabbit's body the preparation redistribution occurs in favor of liver and spleen. The magnetic field applying to the kidneys area leads to the considerable increase of iron concentration in kidneys. As a result of magnetic fields measurements over the rabbit with injected MNP using developed SQUID-magnetometry system, the maps of MNP spatial distribution into the rabbit's body were obtained.
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