Pedersen O, Herskind AM, Kamper J, Nielsen JP, Kristensen K. Rehospitalization for respiratory syncytial virus infection in infants with extremely low gestational age or birthweight in Denmark. Acta Paediatr 2003; 92: 240-242. Stockholm. ISSN 0803-5253 Aim: To determine the risk of rehospitalization for respiratory syncytial virus (RSV) infection during the first 2 y of life in extremely preterm infants. Methods: Records on all rehospitalizations during the first 2 living years of all infants born with gestational age <28 wk or birthweight <1000 g during 1994 and 1995 in Denmark were retrospectively reviewed. Results: Among 240 eligible infants, 43 (18%) had been rehospitalized 48 times owing to RSV. In infants (n = 210) without CLD the risk of rehospitalization for RSV was 16%, whereas in infants with CLD (n = 30) it was 30% ( p = 0.065). Eighteen infants (38%) required respiratory support (supplemental oxygen only 3, continuous positive airway pressure 14, mechanical ventilation 1). Apart from CLD the only factor that could be associated with increased risk of hospitalization for RSV was discharge during autumn ( p = 0.05). No infant died from RSV infection. Conclusion:The high rate of rehospitalization for RSV in extremely preterm infants in Denmark, especially in infants with CLD, should lead to considerations concerning more widespread use of prophylaxis against RSV in these infants.
During the period 1973-83, metroplasty for infertility was performed in 20 cases of symmetric uterine malformation. Apart from a vaginal septum in 2 cases, no other genital malformations were noted. A modified Jones & Jones technique was performed in 16 cases. 3 were unified a.m. Tompkins and 1 a.m. Strassman. No operative complications were noted. Prior to operation, 19 of the 20 women were pregnant, 46 times in all. Of these, 40 ended in spontaneous abortion, 5 in preterm birth, of which 2 infants survived, and 1 in birth at term. Postoperatively, 17 of the 20 women became pregnant, 22 times in all, and of these, 3 ended in spontaneous abortion and 19 with live infants born at term. The metroplasty changed the fetal survival rate from 6.5% prior to operation, to 86.4% after the operation. Pregnancy occurred 15 months, on average, after the operation. Only a few minor complications occurred during the pregnancies. Cesarean section was performed electively in 13 cases and acutely in 3 cases. A vaginal delivery occurred in the last 3 cases. There were only a few abnormal presentations and all the infants were born at term with a mean weight of 3,400 g. Metroplasty seems to be an operation which clearly improves fetal survival rate in women with both symmetric uterine malformations and a history of habitual abortions and/or preterm births. Subsequent pregnancies are not associated with any increased risk of complications.
Es ist yon jeher gebr~uchlich, eine t~eihe der krankhaften Erscheinungen beim ttirntumor als ,,Allgemeinsymptome" zu benennen. Man will damit St0rungen kennzeichnen, die unabh~ngig yore Sitz des Tumors auftreten k~nnen und die meist eine Wirkung des krankhaften Prozesses auf d~s ganze Gehirn oder zum mindesten ~uf grOBere Teile desselben darstellen. Als klinischem Ausdruck einer solchen Allgemeinwirkung begegnen wit einem hinl~nglich bek~nnten Symptomenkomplex (Kopfschmerz, Stauungspaioille , psychische Abweichungen, dann Puls-und Atmungsanomalien, Erbrechert, Kr~mpfe usw.).Die Ursache dieser Erscheinungen wird in der durch den Tumor bedingten intrakraniellen Drucksteigerung gesucht. Man spricht kurz yore I-Iirndruck und versteht d~runter nach Reichardt die klinische AuBerung eines krankhaften Migverh~ltnisses zwischen dem verfiigb~ren Seh~delinnenr~um und den in ibm eingesehlossenen festen und fliissigen Substanzen. Es ist klar, dab dies MiBverh~ltnis eine gewisse GreBe erreichen mug, ehe es kliniseh nachweisb~re Ph~nomene verursacht, daB es Mso einen latenten I-Iirndruek gibt im Gegensatz zu dem uns interessierenden klinisch manifesten ttirndruck.Die erw~hnte Symptomenreihe, die wit in dem klinischen Bild des Hirntumors als Zeichen des gesteigerten intrakr~niel]en Druckes ~uffassen, ist, wie man weiB, einer auBerordentlieh groBen Relativit/~t unterworfen. Nur verh~iltnism~Big selten firtdet man das Hirndrueksyndrom mit seinen versehiedenen Erseheinungen roll ausgebildet. Man sieht immer wieder, dab bei Tumoren, die sieh im
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