Aplasia cutis congenita (ACC) is a rare congenital defect described by the absence of skin and occasionally subcutaneous tissues or bone. The management of ACC varies depending on the lesion size, location and associated abnormalities. Small lesions often heal spontaneously, whereas larger lesions are significant and usually associated with additional anomalies in other organs. This paper reports three cases, which describe large lesions of ACC, presented with other abnormalities (Adams–Oliver syndrome, intestinal obstruction and heart defect). Particular attention should be paid to the patient with large lesions of ACC to investigate more congenital anomalies.
Necrolytic Acral Erythema (NAE) is a rare cutaneous sign for hepatitis C
virus, which generally presents as circumscribed keratotic plaques on
the extremities. Many studies reported NAE in the absence of HCV. This
case presents a female diagnosed with NAE and hypothyroidism in the
absence of HCV infection.
Necrolytic acral erythema (NAE) is a rare cutaneous sign of hepatitis C virus (HCV), which generally presents as circumscribed keratotic plaques on the extremities. Many studies reported NAE in the absence of HCV. This case presents a female diagnosed with NAE and hypothyroidism in the absence of HCV infection.
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