Objectives Aluminum is notorious as a neurotoxic metal.

The excretion of aluminium in urine was significantly increased after intake of analgesics containing aluminium, confirming increased absorption and hence exposure to aluminium with such medication. The effect of aluminium on the kidney was further investigated by study of gene expression in mice. After a single dose of aluminium, an up-regulation of renin gene was found by DNA sequencing of the products of differential display analysis. The up-regulation of renin was confirmed by reverse transcription-polymerase chain reaction (RT-PCR) and Western blotting experiments in the dose dependent treatments and the time course observation after aluminium citrate injection. The up-regulation of the renin expression by aluminium is a strong indication of the influence of aluminium on the renin-angiotensin-aldosterone-system, resulting in possible induction of essential hypertension.

The growth of irregular settlements in Ciudad Juarez has largely contributed to the expansion of the city, where informal city expansion was later transformed to regular urbanization. The reason for this is not far-reaching as the agglomeration of migrants into the city frequently redefined its growth. Simultaneously, the economic significance of the city in the global capital process has further made it a destination point for the engagement of labour from the hinterland of Mexico to central and southern America. This paper investigates the historical context of the emergence of the lived experience amidst poverty and the social exclusion process in Colonia Mexico 68, a settlement to the west of the city of Ciudad Juarez, Chihuahua, Mexico, a vicinity surrounded by multinationals otherwise known as Maquiladoras. The inhabitants are known to be poor and live in poverty and exclusion. The investigation is based on ethnographic research using the Bristol Social Exclusion Model. (BSEM) to measure poverty and social exclusion despite the spatial proximity of the maquilas that empowered the residents. A random sampling of the population was executed through interviews and pictorial evidence. Supporting documented interviews were conducted with the staff of Asentamientos Humanos to further understand the narrative and lived experience of the inhabitants. Luckman and Berger’s subjective reality paradigm was adopted in the execution of the ethnographic findings. It was observed that social policy that focuses on education, training, social security, housing, and health provision would further improve the lives of the inhabitants and foster more forms of inclusion.