Purpose:Patients receiving treatment for benign prostate hyperplasia may have persistent storage symptoms. There has been increasing debate on the precision and accuracy of the International Prostate Symptom Score questionnaires over other questionnaires in evaluating all the complaints of lower urinary tract symptoms (LUTS). The aim of this study was to perform the validity and reliability analysis of the Turkish version of the Internatinal Consultation on Incontinence Questionnaire-Male LUTS (ICIQ-MLUTS).Methods:Linguistic validation was studied (i.e., translation and back translation). Intelligibility was completed between October 2013 and November 2013. Data was collected between November 2013 and March 2014. The stability and reliability of the form were measured with the Cronbach test.Results:In total, 117 male patients were included in the study. At the first visit, the mean age of the patients was 59 years (range, 18–84 years). For reliability, the Cronbach alpha value was 0.798, demonstrating the internal consistency of the form (r>0.7). The internal consistency of each question was examined separately and found to be over 0.7. For the evaluation of test-retest reliability, the test was administered to 116 patients for a second time with an interval of 2–4 weeks. The first and second test scores for each question were found to be correlated (r=0.741).Conclusions:ICIQ-MLUTS is a new questionnaire, which can be used for evaluating male LUTS in Turkey. We believe that the Turkish version of the ICIQ-MLUTS is an important breakthrough in our country.
Objective: The aim of this study was to investigate the effect of serum gonadotropin and total testosterone levels on semen parameters. Materials and Methods: Three hundred and eighty-two patients that applied to a male infertility polyclinic were included in our study. Serum gonadotropin and total testosterone levels and semen parameters of the patients were analyzed during the first visit to the clinic. The reference FSH value was 1.5-12.4 mIU/mL, that of LH was 1.7-8.6 mIU/mL and the reference value for total testosterone was 249-836 ng/dL. Results: While there was no statistically significant difference between the patients with low gonadotropin levels and the controls regarding any of the semen parameters (p > 0.05), there was a strong statistically significant difference between the patients with high gonadotropin levels and the controls regarding sperm concentration (p = 0.000), total motility (p = 0.000), progressive motility (p = 0.000), and morphology (p = 0.000). There was a strong statistically significant difference between the patients with low testosterone levels and the controls regarding total motility (p = 0.012) and progressive motility (p = 0.010), and a weak statistically significant difference in morphology (p = 0.042). There was no statistically significant difference in semen volume or sperm concentration (p > 0.05). There was no statistically significant difference in any of the semen parameters between the patients with high testosterone levels and the controls (p > 0.05). Conclusions: Our findings especially regarding LH and T levels are not in agreement with previous reports. In this regard, there is a need for larger-scale and randomized trials to resolve this discrepancy. KEY WORDS:Gonadotropin; Semen; Testosterone. SummaryNo conflict of interest declared.to testicular obstruction (2) or abnormal hormone levels, leading to dysregulated sperm production. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T) are key hormones in fertility health. FSH and LH are types of 'gonadotropins' that are synthetized in the adenohypophysis of vertebrates due to the effect of gonadotropin-releasing hormone (GnRH). Production of gonadotropins is controlled by T, estradiol (E2), and inhibin B (3, 4). LH binds to receptors on Leydig cells, leading to increased release of intratesticular T. FSH binds directly to Sertoli cells, leading to secretion of many factors crucial for sperm development. As Leydig cells, Sertoli cells, and peritubular cells in the seminiferous tubules are important in spermatogenesis (5), the decrease in FSH and LH production results in reduced testicular function, and infertility. FSH and inhibin B are considered markers of spermatogenesis and Sertoli cell function (6-10). In previous studies, a negative correlation was found between FSH levels and sperm concentration, while a positive correlation was found between inhibin B levels and sperm concentration (10-12). No relationship between semen parameters and LH and T levels was detected (10). The a...
Patients with proximal ureteral stones >10 mm who were treated with URS generally may have a more favorable HRQoL than those treated with SWL in short-term follow-up.
Purpose:To determine the proportion of patients with undetected symptoms of overactive bladder by using the overactive bladder-validated 8 (OAB-V8) screening questionnaire and investigate these symptoms were undetected in female patients who were hospitalized.Methods:We invited 2,250 female patients hospitalized in the Aegean region of Turkey to answer a self-administered questionnaire. The questionnaire included questions on evidence of lower urinary tract symptoms (OAB-V8), relevant medical history, and demographic data. Patients with a total OAB-V8 score≥8 were defined as having OAB symptoms.Results:The proportion of patients with OAB symptoms in this study was 40.6%. Nearly 57% of the patients with OAB symptoms had not been previously admitted to any hospital for lower urinary tract symptoms (LUTS). The two most common reasons why women with OAB symptoms did not admit themselves to a hospital because of LUTS were as follows: “I did not think I had a disease” and “The symptoms did not bother me,” with a response rate of 74.7%. The mean OAB-V8 scores of the patients with these two responses were significantly lower than those of the other patients (P<0.001).Conclusions:This is the first study to demonstrate a significant proportion of women with undetected OAB symptoms. The main reasons the women did not admit themselves to a hospital were their unawareness of the disease and because the LUTS were not bothersome. Public awareness programs on this disease may resolve this problem.
PNL can be effectively and safely administered for the treatment of solitary kidney. In the treatment of large urinary calculi in patients with a solitary kidney, PNL has some advantages such as short surgery duration, less complication, acceptable hemoglobin drawdown and high success rates. According to our study, PNL operation in patients with a solitary kidney is a good option for carefully and poisedly selected cases.
The most impoırtant complication of mumps infedion in adolescent males which can often lead to testicular atrophy is orchiHs. We evaluated the efiideney of intedemn oı 2B in mumps orchitis.Seventeen patients with mumps orchiti:s treated with interfemn oı 2B (3 million units/day for 7 days) to prevent the testimlar atrophy and pain. Mean follow up was 17A months (13~35 months).Scrotal pain and tendemess decreased within 48 hours in 12 patients and testicular swelling disappeared in all of the patients on the fifth day. Testicular atmphy developed in 3 patients.Interfemn oı 2B is effective in the treatment of mumps orchitis, because of decreased rate of atroph_y and alleviation of symptoms in short pe:riodo (Key Words: Paramyxovirus, Intederon oı-2B, Testicular atrophy) ÖZETYeti~kin erkeklerde görülen kabakulak enfeksiyonunun en önemli koplikasyonu or~ittir ve testiküler atrofiye neden olabilir. Testiküler atrofiyi, ağnyı ve i~ gücü kaybını önlemek amacıyla, kabakulak or~iti olan olgularda interferon a 2B'nin etkinliği araştınlım~hr.1 Olgu iki taraflı olmak üzere, toplam 17 kabakulak on~itli olguya 7 gün süreyle, günde 3 milyon IU /SC. Interferon a. 2Bverilmi~ ve olgular ortalama 17.4 ay (13~35) izlenmiştir.12 ilk 48 saat içinde ağrı ve hassasiyetle azalma görülmü~ ve tüm olgularda testisteki şi~lik 5.günde kaybolmuştur. 3 olguda (%17.6) testis atrofisi geli.şm~tir.Semptomları çok kısa sürede yatı~tırması ve atrofi oranını azaltınası nedeniyle interferon oı 2B kabakulak or~itli olguların tedavisinde etkili bulunmuştur.
MATERIAL and METHOD: Between Jamıary 1994~June 1998, 122 patients wiı:h !3upeırficial bladder cance:r were induded in this study. Random biopsies we:re taken :&om each patient during the iniHal TUR RESUL TS: Mean age w as 53 (24-82) Random biopsies we:re posi'tive in 13 patients. There was no significant difference among sl:ages in :regard of pmıiHvity of random biopsieso Ten (77%) of 13 posiiive random biopsy s:Hes were in dose proximity to the iniHal lesiorı.; the rest (%23) had showed different locaHzatiı:mso Inb:acavitary BCG was given if cardnoma i:n-situ (Cis) (53%) was fomı.d on random biopsieso In tumo:rs ıreported as Grade 2 and superfidal (Pt 1 management was changed according to risk fadors hıize, number).CONCLUSION: The finding of Cis and highe:r tumo:r gl'ades on random biopsie § changed our treatment in 70% of om: patients and we stmngly suggest to take random biopsy during the initial surgeryo
Feı:-ruh ZORLU Altmış beş yaşındaki kadın hasta sol yan ağrısı yakınması ile başvurdu.tomografi ile sol böbrekte idrar sızması gösterildi. Bu durum bir çift J kateter yerleştirilerek tedavi edildi. Çift J kateter 4.ncü haftada yerel anestezi ile çıkarıldı. Görüntüleme yöntemleriyle böbrek morfolojisinin normal ol.duğu gösterildL Anahtar Sözcükler: Çift J Kateter, Spontan perirenal ekstravazasyon, Üriner SUMMARY A 65-year old woman visited o ur w ith a complaint of left flank sean n ed of the ki d ney showed perirena! urine extravasation. The di sorder was insertion of a JJ catheter. The JJ catheter was removed on fourth week under local anesthesia. Repeat imaging showed normal renal function and morphology in this case.
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