The study was conducted to assess the prevalence of Hepatitis B surface antigen (HBsAg) among the newly admitted students of University of Jos, Jos Nigeria. A total of 300 newly admitted students were screened using rapid test (Global Rapid Diagnostic Kits USA) for the detection of HBsAg in serum samples from July 2010 to October 2010. The results obtained showed that 50(16.7%) were seropositive to HBsAg. The prevalence of HBsAg was higher in males 34(11.33%) compared to 16(5.33%) in females. Age specific prevalence was significantly higher in the age bracket 25-29, with 16(28.57%) and the lowest was found in the age bracket 15 -19 years with 12(17.39%). The most important risk factors in the acquisition of HBsAg as revealed in this study appear to be: Family History of hepatitis, 11(36.6%), those with multiple sexual partners 4(13.79%), blood transfusion 3(13.64%), and tribal mark 3(13.04%). The prevalence of HBV recorded among newly admitted students in this study is probably a reflection of the situation in Nigerian Universities. Therefore, urgent preventive measures should be taken to set up campaign against transmission of HBV in University of Jos and the general population. To lower HBV prevalence, an adequate program of active screening and vaccination for students should be implemented, followed by a universal active immunization program.
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