Significant prevalence and decline in quality of life caused by psoriasis in combination with the lack of etiotropic methods of its treatment, put this disease, in terms of relevance for modern medicine on a par with diabetes, hypertension, asthma etc. That is, there is a need to find easily accessible markers that would determine the susceptibility to this disease. The aim of the study was to establish the differences in the skinfold thickness between healthy and/or psoriatic Ukrainian men depending on the severity of the disease without and taking into account the somatotype. For 32 Ukrainian men of the first mature age, patients with mild psoriasis and 68 men with severe psoriasis (according to the PASI index) were determined skinfold thickness according to Bunak and determined the somatotype according to the Heath-Carter scheme. The control group consisted of 82 healthy men of similar age, selected from the database of the research center of National Pirogov Memorial Medical University, Vinnytsya. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. It was found that in patients with mild or severe psoriasis of men without division into somatotypes and in representatives of the mesomorphic somatotype compared to healthy men, the skinfold thickness is significantly higher at the lower angle of the scapula, abdomen and side, and significantly lower on the back and front of the shoulder, chest and thighs. When comparing the skinfold thickness between patients with mild or severe psoriasis of endo-mesomorphic somatotype with healthy men of similar somatotype, we found larger values of the skinfold thickness under the lower angle of the scapula (only with mild course), on the abdomen and side, and also smaller values of the skinfold thickness on the posterior surface of the shoulder and only in representatives with severe psoriasis – on the anterior surface of the shoulder, chest and thigh. Between patients with different degrees of severity of dermatosis both without distribution, and with distribution on various somatotypes of reliable or tendencies of differences of skinfold thickness are not revealed. Thus, there are pronounced differences in most indicators of the skinfold thickness between healthy and patients with mild or severe psoriasis of Ukrainian men of the first mature age, both without distribution and with the division into different somatotypes.

Annotation. The constitutional approach is a valuable tool in the hands of practicing dermatologists, which allows an individual approach to the diagnosis and treatment of patients with psoriasis. The aim of the study was to examine the differences in total, longitudinal and transverse body sizes between healthy and/or psoriatic men depending on the severity of the disease. Anthropometric examination according to Bunak was performed for 32 men of the first mature age in patients with mild and 68 men with severe psoriasis. The PASI index was used to clinically assess the severity and area of psoriatic lesions. As a control from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya anthropometric data of 82 practically healthy men of the same age group were selected. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. In patients with mild and severe psoriasis compared with healthy men found: lower values – pubic height (by 3.2 % and 5.4 %) and trochanter (by 8.2 % and 7.0 %) anthropometric points, shoulder width (by 19.6 % and 19.0 %) and the width of the distal epiphysis of the shin (by 5.2 % and 4.8 %); greater values – body weight (by 20.1 % and 17.5 %), body length (by 1.7 % in mild course), body surface area (by 10.0 % and 7.8 %), height of suprasternal (by 3.0 % and 1.5 %), acromial (by 2.3 % and 1.0 %) and finger (by 6.1 % and 4.4 %) anthropometric points, width of the distal epiphysis of the shoulder (by 6.9 % and 5.7 %), forearm (by 3.3 % in mild course) and thigh (by 10.3 % and 7.1 %), mid-thoracic diameter (by 16.5 % and 16.3 %), transverse lower thoracic diameter (by 16.5 % and 15.7 %), anterior-posterior mid-thoracic diameter (by 17.7 % and 20.2 %), interspinous (by 12.2 % and 12.1 %), intercristal (by 13.4 % and 11.7 %) and intertrochanteric (by 11.3 % and 10.4 %) distances. Differences in the studied body size in patients with varying degrees of psoriasis found. Thus, in patients with mild psoriasis, compared with patients with severe psoriasis, higher values were found for: body length (by 1.6 %); heights of suprasternal (by 1.5 %), pubic (by 2.1 %) and finger (by 1.4 %) anthropometric points; width of the distal epiphysis of the forearm (by 2.3 %). Thus, pronounced differences in total, longitudinal and transverse dimensions between healthy and patients with mild and severe psoriasis were revealed by Ukrainian men of the first mature age. Between patients with varying degrees of severity of dermatosis, most differences are found only for longitudinal body size.

The purpose of the work is to analyze the scientific literature on the constitutional features of the occurrence and course of psoriasis. The analysis of modern scientific literature in the scientific databases PubMed, eLIBRARY.RU and Web of Science was carried out. A review of the literature indicates the current state of the problem of such a disease as psoriasis, which is not only a skin lesion but also a serious socio-psychological problem. Given its chronic nature, lack of etiopathogenetic treatment, and knowing the trigger factors in the right way, it would be a good idea to look for early predisposition for the disease and to form risk groups for such individuals. Ideal in terms of efficiency and cheapness, given the results of the above studies, could be anthropological studies. The study of the constitutional features of the occurrence and course of psoriasis for the population of Ukraine is thus a priority and topical area of research.

Annotation. Exacerbation and aggravation of psoriasis increases the chances of neurosis, depression, can significantly impair mental health through social stigma and leads to social isolation and maladaptation, a significant reduction in quality of life. Studying this problem from the standpoint of comparative assessment of the distribution of character accentuations in patients with different dermatoses can provide insight into how a certain level of adequacy of psychological adaptive response is associated with organic pathological process or genetically existing expression of certain traits. The aim of the study was to found the features of indicators of expression and features of accentuated personality traits in men with psoriasis without taking into account somatotype and in representatives of meso- and endo-mesomorphic somatotypes. Men aged 22 to 35 years, patients with psoriasis (n=100, including 32 with mild and 68 with severe course) at the Department of Skin and Venereal Diseases with a course of postgraduate education National Pirogov Memorial Medical University, Vinnytsya and Military Medical Clinical Center of the Central Region, conducted an anthropometric survey by V. V. Bunak Estimation of the expression and features of accentuated personality traits made according to G. Shmishek The reliability of the difference between the values between the independent quantitative values was determined using the U-Mann-Whitney test. In healthy subjects, taking into account and without taking into account the somatotype, it is seen that the type of physique did not significantly affect the severity of individual traits and their combinations in this group of people. With the increase in the course of psoriasis among subjects without somatotype, there is a decrease in the percentage of persons with hyperthymic and demonstrative and an increase – with emotional, pedantic, anxious, cyclothymic, excitable, dysthymic and exalted type of character accentuation; among patients of mesomorphic somatotype there is a decrease in the percentage of people with stuck and demonstrative and an increase – with emotional, pedantic, anxious, cyclothymic, excitable, dysthymic and exalted type of character accentuation; among patients of endo-mesomorphic somatotype there is a decrease in the percentage of people with hypertension and an increase – with stuck, demonstrative and excitable type of character accentuation. All this maintains a pathologically high level of affective tension, which disrupts the autonomic balance in the body, can be a pathogenic factor in the development of psychosomatic illness and leads to ineffective treatment of psoriasis.

Psoriasis, despite its seemingly simple clinic and course, is at the same time a complex socio-economic phenomenon that causes stigmatization of people with this disease. The use of constitutional markers to predict the risk and severity of psoriasis could be a promising way to alleviate this problem. The aim of the study was to establish and analyze the differences in girth body sizes between healthy and/or psoriatic Ukrainian men of different somatotypes depending on the severity of the disease. On the basis of the Military Medical Clinical Center of the Central Region and the Department of Skin and Venereal Diseases with a course of postgraduate education of National Pirogov Memorial Medical University, Vinnytsya, the determination of body sizes’ in men aged 22 to 35 years, suffering from psoriasis of mild (n=32) and severe (n=68) course was carried out. Clinical assessment of the severity and area of psoriatic lesions was performed using the PASI index. Determination of somatotype was performed according to the Heath Carter method. As a control from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya anthropometric data of 82 practically healthy men of the same age group were selected. Statistical processing of the obtained results was performed in the license package "Statistica 5.5" using non-parametric evaluation methods. Compared with healthy men of the corresponding somatotypes, it was found: in patients with mild and severe psoriasis men of mesomorphic somatotype – significantly higher, or a tendency to greater values of almost all girth body sizes (except foot girth, and only in patients with mild course – girth of forearms in the lower part); only in patients with mild psoriasis men of endo-mesomorphic somatotype – significantly higher, or a tendency to higher values of almost all girth body sizes (except for the girth of the foot and lower leg in the lower part). In patients with psoriasis men of endo-mesomorphic somatotype with a mild course of the disease significantly higher, or a tendency to greater values than in patients with a similar course men of mesomorphic somatotype shoulder girth in stressed and unstressed state, forearms, upper and lower arms thighs, hips, shins in the upper part, neck, waist and all the girths of the chest; and in patients with psoriasis men of mesomorphic somatotype with a severe course of the disease – only tendencies to greater values than in patients with a similar course men of endo-mesomorphic somatotype girth of thighs and shin in the upper part. In patients with mild psoriasis men, the differences in body sizes between mesomorphic and endo-mesomorphic somatotypes are similar to healthy men, but are more pronounced. When comparing the girth of the body between psoriasis patients Ukrainian men of the corresponding somatotypes, representatives of the mesomorphic somatotype with severe disease have significantly higher, or a tendency to greater values than with mild course, the girth values of the forearms at the top, neck, waist and all around chest, as well as the tendency to lower values of the girth of the shin. The established pronounced differences in the girth sizes of the body provide an opportunity to identify risk groups for the occurrence and features of psoriasis.