Background: Pig rabies is uncommon and there is paucity of information on rabies in pigs in West African countries other than Nigeria. This communication presents a case of dog associated pig rabies in Adidome, Ghana. Materials and Methods: Case history, Dog assessment in adjoining communities, human exposure, clinical presentations and mortality in affected pigs were evaluated using standard techniques. Laboratory screening of brain samples collected was by Fluorescent antibody technique. Results: Stray dog bitten affected pigs showed anorexia, constipation, hyper excitation, twitching of head, roaring and foaming with resultant category 1 and 11 human exposure, 17% mortality and 75% case fatality rate. Laboratory examination of swine brain specimens tested positive for Rabies virus using Fluorescent Agglutination Test.
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