Urinary Schistosomiasis is endemic in Nigeria and continues to pose public health challenges especially in inhabitants of rural areas. This study was conducted in an attempt to determine the co-infection of Schistosoma haematobium and S. intercalatum in Apojola Community area of Abeokuta North LGA of Ogun State, Nigeria. Urine samples were analyzed in the Laboratory using sedimentation/centrifugation technique to determine schistosoma eggs. Positive urine samples were further confirmed using Ziehl-Neelsen (zn) staining method for differentiating S. haematobium from S. intercalatum eggs. The results indicate that 79 (52.7%) of the urine samples collected were positive for schistosoma eggs. Among the positive urine samples, 62% had S.haematobium while 38% had S. intercalatum eggs. Infections were found to be high in males 39 (55.7%) than female 40 (50%). Villagers who were <13 years of age had the highest prevalence rate of infection. Co-infection of S. haematobium and S. intercalatum among the villagers was established in the study and was observed to be highest in the age group <13years, compared to other age group. The study confirmed the endemicity and the co-infection of S. haematobium and S. intercalatum in the study area. It is therefore recommended that water control, sanitation and snails elimination as well as community-based programs are urgently needed to reduce S. haematobium and S. intercalatum infection.
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