Context. Recent results strongly challenge the canonical picture of massive star winds: various evidence indicates that currently accepted mass-loss rates,Ṁ, may need to be revised downwards, by factors extending to one magnitude or even more. This is because the most commonly used mass-loss diagnostics are affected by "clumping" (small-scale density inhomogeneities), influencing our interpretation of observed spectra and fluxes. Aims. Such downward revisions would have dramatic consequences for the evolution of, and feedback from, massive stars, and thus robust determinations of the clumping properties and mass-loss rates are urgently needed. We present a first attempt concerning this objective, by means of constraining the radial stratification of the so-called clumping factor. Methods. To this end, we have analyzed a sample of 19 Galactic O-type supergiants/giants, by combining our own and archival data for H α , IR, mm and radio fluxes, and using approximate methods, calibrated to more sophisticated models. Clumping has been included into our analysis in the "conventional" way, by assuming the inter-clump matter to be void. Because (almost) all our diagnostics depends on the square of density, we cannot derive absolute clumping factors, but only factors normalized to a certain minimum. Results. This minimum was usually found to be located in the outermost, radio-emitting region, i.e., the radio mass-loss rates are the lowest ones, compared toṀ derived from H α and the IR. The radio rates agree well with those predicted by theory, but are only upper limits, due to unknown clumping in the outer wind. H α turned out to be a useful tool to derive the clumping properties inside r < 3. . .5 R . Our most important result concerns a (physical) difference between denser and thinner winds: for denser winds, the innermost region is more strongly clumped than the outermost one (with a normalized clumping factor of 4.1 ± 1.4), whereas thinner winds have similar clumping properties in the inner and outer regions. Conclusions. Our findings are compared with theoretical predictions, and the implications are discussed in detail, by assuming different scenarios regarding the still unknown clumping properties of the outer wind.

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Abstract. Broad-band UBV JHKLM data have been obtained at the time of the quiescent orbital photometric maximum of the classical symbiotic binary system Z And and at some epochs of its 2000-2002 active phase. The data of the active phase are related to the time of the optical maximum and after it when the star was returning to quiescence. Broad-band quiescent RI photometry from the literature was also used to obtain the parameters of the cool component of this binary. All of these data suggest that the hot compact component has undergone a major expansion and the emission measure of the circumbinary nebula has also increased. Some mechanisms for interpretation of the outburst are reviewed.

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