Cardiac arrhythmia relating to hypoglycemia is suggested as a cause of death in diabetic patients. This article introduces electrocardiographic (ECG) parameters for artificially induced hypoglycemia detection. In addition, a hybrid technique of swarm-based support vector machine (SVM) is introduced for hypoglycemia detection using the ECG parameters as inputs. In this technique, a particle swarm optimization (PSO) is proposed to optimize the SVM to detect hypoglycemia. In an experiment using medical data of patients with Type 1 diabetes, the introduced ECG parameters show significant contributions to the performance of the hypoglycemia detection and the proposed detection technique performs well in terms of sensitivity and specificity.
Severe hypoglycemia is potentially life-threatening. This article introduces a novel hypoglycemia detection strategy using a hybrid particle swarm -based fuzzy support vector machine (SFisSvm) technique. The inputs of this system are six electrocardiographic (ECG) parameters. The system parameters of SFisSvm are optimized using a particle swarm optimization method. The proposed hypoglycemia detector system is a combination of two subsystems, namely, fuzzy inference system (FIS) and support vector machine (SVM). Two most significant inputs, heart rate and RTp c are fed to FIS, and its output is used for input of the SVM. The other ECG parameters and the output of FIS are fed to SVM and, then, are classified to indicate the presence of hypoglycemia. In this study, three and five membership functions are investigated for FIS. Furthermore, radial basis function (RBF), sigmoid and linear kernel functions are employed for mapping the inputs to high dimensional space in SVM. Performances of SFisSvm with different kernel functions are compared. As conclusion, the performance of SFisSvm is found with 75.19%, 83.71% and 79.33% in terms of sensitivity, specificity and geometric mean.
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