Clozapine is regarded as a second-line and in some cases last-line antipsychotic known for its common life-threatening side effects, such as agranulocytosis, constipation and cardiomyopathies, but rarely haematemesis. We report a case of severe haemetemesis in a chronic schizophrenic patient managed with clozapine. The patient was a 46-year-old male being managed for chronic schizophrenia with treatment resistance who developed sudden severe haematemesis following commencement of clozapine for 6 weeks. The patient had 1.1 l of blood transfusion. The relevant literature is reviewed. Clozapine can be associated with a life-threatening haematemesis. Psychiatrists and other medical specialists need to be alert to the fatality of clozapine-induced haematemesis in the treatment of psychiatric disorders.
Background:Several studies have shown a high prevalence of drug and substance abuse across the Universities and Secondary schools in Nigeria.
AIM:To conduct an awareness program among Secondary School students in commemoration of Mental Health Day 2022Methodology: Three (3) Secondary Schools were selected within Abeokuta, the capital of Ogun state, Southwest Nigeria. An awareness program was organized through health talks on the effect and prevention of drug/substance abuse. It was a didactic and interactive session with the students.Result: Some students who abuse substances were discovered and a drug abuse ring was also discovered. Through the management of schools visited there was easier networking with other schools and appeal for regular visits solicited by the schools.
Conclusion:Appreciation to the Sebastian Family and the University of Wisconsin for their great work on mental health advocacy globally. Likewise, all the staff of the visited schools are highly appreciated for their cooperation, while not unmindful of the efforts of all team members who have put in their best to see that this year's program was successful.Recommendation:There is a need for continuous sensitization to other schools and working with school authorities in the area of rehabilitation of identified drug/substance abusers.
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