Acute ventricular demand pacing (VVI pacing) is clearly associated with attenuation of FMD in patients with atrial-based pacing systems. The attenuation of endothelial vasodilation might have a role in hemodynamic and clinical deterioration in patients with VVI pacemakers.
Venous thromboembolism is a common complication in patients with cancer and an important cause of morbidity and mortality. Idiopathic thrombosis, migratory or recurrent thrombophlebitis may be the first manifestation of an occult malignancy. While deep venous thrombosis and pulmonary embolism are the most common thrombotic conditions in patients with malignant disease, tumor thrombus may be seen in inferior vena cava, mainly in patients with renal cell carcinoma, hepatocellular carcinoma, testicular tumors or adrenal carcinoma. Although pancreatic cancer is one of the cancers that are most strongly associated with thrombotic complications along with cancers of ovary and brain, there has been no report about presence of thrombus in the inferior vena cava in pancreatic cancer. We report a female patient with pancreatic cancer associated with tumor thrombus extending from the inferior vena cava to the right atrium.
Coronavirus Disease 2019 (COVID-19)", kardiyovasküler sistemi doğrudan veya dolaylı yollardan etkileyebilmektedir. COVID-19 konakçı hücrelerini anjiyotensin dönüştürücü enzim-2 (ACE-2) reseptörleri üzerinden enfekte etmektedir. ACE-2; alveoler epitel hücrelerinde, ince bağırsak epitel hücrelerinde, arteriyel ve venöz endotelyal ve düz kas hücrelerinde bulunmaktadır. Enfeksiyonun yol açtığı arteriyel ve venöz tromboembolizme bağlı olarak akut koroner sendromlar ve venöz tromboembolizm gelişebilmekte, miyokardite ikincil olarak gelişen akut kalp yetersizliği COVID-19 hastalığının seyrinde görülebilmektedir. Ayrıca COVID-19 için kullanılan ilaçlar ve hastalığın kendisi de aritmiye neden olabilmektedir. Kardiyovasküler risk faktörleri olan (erkek cinsiyet, ileri yaş, diyabet, hipertansiyon) veya kardiyovasküler hastalığa sahip COVID-19 hastalarında hastalık daha ağır seyretmekte ve daha fazla mortalite izlenmektedir.
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