The addition of intranasal ketamine to oral midazolam significantly improved the quality of induction and reduced sevoflurane-induced emergence agitation, in children undergoing urological surgery.
Objective: The purpose of our study is to compare two different ventilation modes-pressure support ventilation (PSV) and volume support ventilation (VSV)-as the means of weaning.
Methods:Sixty patients were enrolled in our study. Patients were randomized in to two groups. For the PSV group, FiO 2 and airway pressure values were adjusted in order to sustain PaCO 2 : 35-45 mm Hg, pH>7.32, 6-8 mL kg -1 TV (tidal volume), and saturation >92%. For the VSV group, FiO 2 , TV, respiration frequency (f ), and peak pressure were adjusted to obtain PaCO 2 : 35-45 mm Hg, pH>7.32, 6-8 mL kg -1 TV, saturation >92%, and PO 2 >60 mm Hg. Every morning, spontaneous breathing was tried in those patients. The patients were extubated after 2 hours of T-piece breathing. The patients who failed spontaneous respiration with the T-piece were returned to mechanical ventilation. Assisted ventilation time (ART), mechanical ventilation time (MRT), total T-piece time (TTT), total weaning time (TWT), and sedation need (SN) values were recorded. "T-test" and "Chi-square" methods were used for statistical analysis.Results: In our study, the mean ART was 82.60 hours for the PSV group and 56.03 hours for the VSV group (p<0.041). TWT was 93.30 hours for the PSV group and 56.03 hours for the VSV group (p<0.035). The mean TTT was 7.67 hours for the PSV group and 3.83 hours for the VSV group (p<0.007). Nineteen patients in the PSV group and 9 patients in the VSV group required sedation during the weaning process (p<0.01).
Conclusion:In the weaning period, VSV seems to be more advantageous than PSV.Key Words: Weaning, ventilatory support, assisted ventilation modes Abstract Introduction
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