A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide, [ F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.
A brief outlook on low-energy nuclear physics is presented. Selected recent developments in nuclear structure theory are highlighted and a few open questions are discussed.
In this study the total efficiency of the NaI(Tl) detector have been calculated by using Geant4 based GATE simulation program. The simulation was performed using point and disc isotropic gamma-ray sources at various distance between source and detector in the photon energy range 50-3000 keV. Results were compared with different analytical and Monte Carlo calculations obtained in the time of the periods 1958-2018. The calculated and simulated data indicated good agreement with finding more sensitive GATE simulation result in the lower energy range from 50 keV to 150 keV.
Mammography and standard breast imaging devices in the hospital are not enough an accurate diagnosis of breast cancer especially over the 40 years old and overweight women. The spatial resolution of the scintillation detector system is a highly important parameter for nuclear medical imaging. GATE simulation program, based on GEANT4, is used for the investigation of the SPECT system with different scintillations which are commonly used in the imaging device. Medical images for the point source are obtained by ImageJ software and image properties such as spatial resolution and mean grey values are compared for the several scintillations. This research shows that the spatial resolution value for GAGG(Ce), relatively new scintillation material, is very close to SrI which is one of the expensive scintillators. NaI, LaBr and CeBr are extremely hygroscopic and not easy to be packaging with a specific shape. Therefore, GAGG(Ce) are found to be encouraging result to be a part of the novel medical image device. This study also shows how important using collimator in front of the scintillation material for obtaining a meaningful image and how improved the image quality using the array scintillator instead of one single block. There is not any research regarding medical imaging obtained by GAGG(Ce) scintillation material in GEANT4 simulation, so this research data presented are the first of their kind.
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