Background and aim: To assess the long-term functional outcomes of operative treatment for tarsal tunnel syndrome (TTS) and determine the factors that are associated with favorable and unfavorable clinical results. Patients and methods: Sixty six patients (71 feet) who had undergone tarsal tunnel release (TTR) operation between 2000 and 2009 were recalled for a follow-up evaluation by a physiatrist to determine the outcome. The subjective complaints of the patients were re-evaluated using two different questionnaires: the foot function index (FFI) and a structured questionnaire. Results: The mean age of the patients was 51.67 ± 13.07 (range 21-84) years. The mean follow-up time was 54.36 ± 15.72 (range 12-96) months. Outcomes in terms of patient satisfaction were 45.1%-very satisfied (VS), 16.9%-moderately satisfied (MS), 19.7%-somewhat satisfied (SS), and 18.3%-not satisfied. Prognostic indicators of poor results in univariate analysis were older age, obesity, longer disease duration, coexisting lower back pain (LBP), plantar fasciitis, diabetes mellitus (DM), and/or carpal tunnel syndrome (all p 0.05). Conclusion: LBP and DM were the most significant factors associated with unfavorable clinical results. The majority of the patients' symptoms improved following TTR operation.
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