A new Cd(II) complex with a tridentate Schiff base derivative which was obtained from condensation of gallic hydrazid with 2-acetylpyridine has been prepared. The structure of the ligand 3,4,5-Trihydroxybenzoic acid[1-(pyridyl)-ethylidene]hydrazone (GAPy) was confirmed using the X-ray structure analysis. The elemental analysis, FTIR, UV-Vis, 1 H NMR spectral and Thermal analysis indicates that the Schiff base ligand GAPy is a tridentate ligand which is coordinated with the Cd(II) complex through N,N and O atoms. Thus, the acetate ion is a bidentate ligand that is coordinated with the metal ion through two O atoms.Keywords: Schiff base derivatives, Cd(II) complexes, hydrazone derivatives complexes, spectroscopic characterization.e-mail: drshaimaa611@yahoo.com INTRODUCTIONSchiff bases from gallic hydrazides are well known as polydentate ligands which are considered as an important class of ligands in coordination chemistry. 1 Thus, gallic hydrazide and its substituted derivative have been prepared and characterized during the past few years. 2-9 Metal complexes of tridentate Schiff base ligands with donor atoms such as (NNO) have attracted considerable attention because they display anti-fungal activity against various fungal such as Aspergillus Flavus, Trichophyton longifusus, Candida albicans and Microsporum canis. 4,10 Moreover, these complexes display remarkable antitumor activity against HL60 and A-549 cancer cell lines, and also display antioxidative, anti-inflammatory, antimutagenic, anticarcinogenic and antiallergic activities. 11 The hydrazone group has two imino and amino nitrogen atoms whose valance electrons differ in their degree of hybridization. The possibility of chelate formation via a hydrogen bond between the nitrogen atom of a gallic hydrazones and the hydrogen atom of the OH group of salicyldehyde has been reported. [12][13][14][15] Since little work has been reported on Cd(II) complex containing 3,4,5-Trihydroxybenzoic acid[1-(pyridyl)-ethylidene]hydrazide. We prepared the schiff base from gallic hydrazide and synthesized the complex with Cd(II) ion. Uv-Vis, IR, and TGA spectroscopy as well as X-ray diffraction were used to examine the coordination site of the ligand and the geometry of the complex. EXPERIMENTAL Techniques and MaterialsAll chemicals were obtained from commercial sources and were used without further purifications (Cd(II)acetate, gallic hydrazide, 2-acetylpyridine, ethanol, DMSO, DMF, Triethylamine, KBr) from Merck (Darmstadt, Germany).Infrared spectra were obtained using KBr discs (4000-400 cm -1 ) on a Perkin-Elmer FT-IR spectrometer (Kyoto, Japan). Measurement of UV-Vis spectra were carried out using a Shimadzu UV-VIS spectrophotometer UV-160 (Hitachi, Tokyo, Japan) in 10 -3 M DMSO solution. Thermal analysis of the complex was performed on a Perkin-Elmer Pyris Diamond DTA/TG Thermal System under a nitrogen atmosphere at a heating rate of 10 o C/min and within a heating range of 30-900 o C. Elemental analysis (C, H, N) was performed by using a Flash EA 1112 Series el...
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