Purpose To determine the efficacy and safety of accelerated corneal crosslinking in children with keratoconus. Methods Two hundred twenty-nine eyes of 146 patients aged 16 years and younger with keratoconus were included in this study. The best corrected visual acuity (BCVA), spherical and cylindrical values, keratometric values (K1-K2), steepest keratometric value (Kmax), and thinnest corneal thickness (TCT) of the patients were recorded pre-operatively and post-operatively at 1, 3, 6, and 12 months. Ocular and systemic diseases associated with keratoconus were also recorded. Results The results showed stabilization of refractive BCVA in the first postoperative month, with a slight improvement over time. The Keratometric values (K1 and K2) and Kmax remained stable throughout the follow-up period. The minimum central corneal thickness initially decreased but stabilized 12 months after crosslinking. No complications, such as corneal opacity, non-healing epithelial defects, or corneal infections, were observed during the follow-up. Allergic conjunctivitis (30.8%), congenital cataracts (1.36%), nystagmus (0.68%) and blepharoptosis (0.68%), were the most common ocular co-morbidities. Conclusion The paediatric age group is at high risk due to the rapid and aggressive nature of the disease. According to the results of our study, corneal crosslinking treatment in childhood limited the progression of keratoconus and at the same time provided a slight increase in visual acuity.
Background: This study aims to assess the impact of preoperative deviation on surgical success and sensory function in infantile exotropia. Furthermore, to assess the effects of late surgical timing in these patients.Materials and Methods: This retrospective study evaluated 16 subjects with infantile exotropia that underwent surgical management between 2012 and 2018. Patients with deviation ≤ 50 prism diopters (PD) were added to Group 1, and Patients with deviation > 50 PD were added to Group 2 to assess the impact of preoperative deviation on surgical success and sensory function. The surgical success is descri-bed as ≤5 PD esotropia and ≤10 PD exotropia for patients. The Titmus stereopsis and Worth 4-Dot tests were used for sensory function assessment.Results: The average preoperative deviation was 50,63 ± 18,7 PD (20-90). The median age at the time of surgery was 73 (24-400) months. Surgical success was observed in 75% of the patients after the first surgery, and surgical success was observed in all patients after the second surgery. The sensory function was assessed in 11 testable patients (68.7%), of which 5 (45.4%) fusion was observed in the Worth 4-Point test, and 2 (18.1%) achieved measurable stereopsis. While the preoperative deviation had an effect on fusion, it had no effect on stereopsis and surgical success(p=0,015; p=0,45; p=0,77 respectively).Conclusions: The smaller preoperative deviation may be associated with a higher rate of sensorial fusion development. Furthermore, relatively high surgical success can be achieved with late surgical timing in these patients.Keywords: Exotropia, Preoperative deviation, Strabismus, Stereopsis
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