Adult rats starved for 48 h received a daily injection of thyroxine over a 3-day
period before they were killed. When compared to nourished animals, starvation provoked a
4- to 5-fold increase in immunoreactive lactase protein, which paralleled a similar stimulation
of lactase activity in the brush border membranes of the proximal jejunum. Exogenous
thyroxine completely inhibited the starvation-induced increase in immunoreactive lactase
protein in both the intracellular and the brush border membranes.
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