akotsubo syndrome (TTS) is a disorder known to be triggered by several stresses. [1][2][3][4][5] The stresses that have been associated with TTS can be primarily divided into 2 categories: physical stress or mental stress. Natural disasters can be a type of mental stress and are known to trigger the onset of TTS. 6-8 The Great East Japan earthquake (GEJ-E) disaster and massive tsunami, which occurred at 14:46 hours on March 11, 2011, was a magnitude 9.0 earthquake with an epicenter off the coast of Sanriku. The maximum seismic intensity of the earthquake was 7 in Kurihara, Miyagi Prefecture, and the tsunami reached up to ≥9.3 m in Soma, Miyagi Prefecture. A total of 19,630 people died, 2,569 were recorded as missing, 6,230 were injured, and 115,8976 homes were damaged on March 1, 2018. The earthquake has been reported as having a large impact on the development and treatment of various cardiovascular diseases. 9-17 At first, the GEJ-E disaster was also thought to have increased the number of cases of TTS, but a short-term report from Miyagi Prefecture in 2013 indicated that there was no obvious increase. 18 Even nearly 10 years after the disaster, people are still living in temporary housing, and there are concerns that the effects of the disaster may have led to chronic stress. A previous study reported that the incidence of acute heart failure was increased for a long time after the GEJ-E disaster. 19 However, no studies have compared the incidence of TTS in coastal and inland areas and the long-term course of TTS after the GEJ-E disaster.This study aimed to investigate (1) the incidence and Editorial p ????
Background Previous studies demonstrated Takotsubo syndrome (TS) was easy provoked by earthquake disaster. However, a previous other regional report demonstrated TS was not increased after 2011 east Japan earthquake disaster. The purpose of this study was to clarify incidence of TS after the earthquake disaster in Iwate prefecture during long term period. Method Consecutive hospitalized TS patients were registered during 8 years between 2009 and 2016 in our medical university and five Iwate prefecture hospitals. Moreover, patients were divided into two groups, i.e., those with the inland and those with tsunami-stricken area groups. Prevalence of TS were calculated by standard incidence ratio (SIR) before and after the earthquake disaster. Moreover, long-term prognosis in the both groups was compared using Kaplan-Meier analysis. Results A total of 112 TS (male 25 and female 87) were registered from acute coronary syndrome registry in each hospital (n=4,163). Averaged age was 75.3 year-old. A total number of TS just after the two months of the earthquake (March and April 2011) was nine and significance monthly variation was observed comparing with the other months (p=0.029). SIR before and after the disaster is as following Figure. There were no significant differences for long-term prognosis between the two groups (p=0.20). Conclusion Incidence of TS was increased in acute phase after east Japan earthquake disaster. However, significance increases were maintained during long-term period, although number of TS was decreased after acute phase. TS is increased not only acute but also chronic phase after the serious earthquake disaster. Standard incidence ratio Funding Acknowledgement Type of funding source: None
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