Diagnosis and treatment of circadian rhythm sleep-wake disorders both require assessment of circadian phase of the brain’s circadian pacemaker. The gold-standard univariate method is based on collection of a 24-hr time series of plasma melatonin, a suprachiasmatic nucleus-driven pineal hormone. We developed and validated a multivariate whole-blood mRNA-based predictor of melatonin phase which requires few samples. Transcriptome data were collected under normal, sleep-deprivation and abnormal sleep-timing conditions to assess robustness of the predictor. Partial least square regression (PLSR), applied to the transcriptome, identified a set of 100 biomarkers primarily related to glucocorticoid signaling and immune function. Validation showed that PLSR-based predictors outperform published blood-derived circadian phase predictors. When given one sample as input, the R2 of predicted vs observed phase was 0.74, whereas for two samples taken 12 hr apart, R2 was 0.90. This blood transcriptome-based model enables assessment of circadian phase from a few samples.DOI: http://dx.doi.org/10.7554/eLife.20214.001

This paper presents a novel fully automatic bi-modal, face and speaker, recognition system which runs in real-time on a mobile phone. The implemented system runs in real-time on a Nokia N900 and demonstrates the feasibility of performing both automatic face and speaker recognition on a mobile phone. We evaluate this recognition system on a novel publicly-available mobile phone database and provide a well defined evaluation protocol. This database was captured almost exclusively using mobile phones and aims to improve research into deploying biometric techniques to mobile devices. We show, on this mobile phone database, that face and speaker recognition can be performed in a mobile environment and using score fusion can improve the performance by more than 25% in terms of error rates.

Abstract-Rendering a face recognition system robust is vital in order to safeguard it against spoof attacks carried out by using printed pictures of a victim (also known as print attack) or a replayed video of the person (replay attack). A key property in distinguishing a live, valid access from printed media or replayed videos is by exploiting the information dynamics of the video content, such as blinking eyes, moving lips, and facial dynamics. We advance the state of the art in facial anti-spoofing by applying a recently developed algorithm called Dynamic Mode Decomposition (DMD) as a general-purpose, entirely data-driven approach to capture the above liveness cues. We propose a classification pipeline consisting of DMD, Local Binary Patterns (LBP), and Support Vector Machines (SVM) with a histogram intersection kernel. A unique property of DMD is its ability to conveniently represent the temporal information of the entire video as a single image with the same dimensions as those images contained in the video. The pipeline of DMD+LBP+SVM proves to be efficient, convenient to use, and effective. In fact only the spatial configuration for LBP needs to be tuned. The effectiveness of the methodology was demonstrated using three publicly available databases: print-attack, replay-attack, and CASIA-FASD, attaining comparable results with the state of the art, following the respective published experimental protocols.

Fusing the scores of several biometric systems is a very promising approach to improve the overall system's accuracy. Despite many works in the literature, it is surprising that there is no coordinated effort in making a benchmark database available. It should be noted that fusion in this context consists not only of multimodal fusion, but also intramodal fusion, i.e., fusing systems using the same biometric modality but different features, or same features but using different classifiers. Building baseline systems from scratch often prevents researchers from putting more efforts in understanding the fusion problem. This paper describes a database of scores taken from experiments carried out on the XM2VTS face and speaker verification database. It then proposes several fusion protocols and provides some state-of-the-art tools to evaluate the fusion performance.

Abstract-A new multimodal biometric database designed and acquired within the framework of the European BioSecure Network of Excellence is presented. It is comprised of more than 600 individuals acquired simultaneously in three scenarios: 1) over the Internet, 2) in an office environment with desktop PC, and 3) in indoor/outdoor environments with mobile portable hardware. The three scenarios include a common part of audio/video data. Also, signature and fingerprint data have been acquired both with desktop PC and mobile portable hardware. Additionally, hand and iris data were acquired in the second scenario using desktop PC. Acquisition has been conducted by 11 European institutions. Additional features of the BioSecure Multimodal Database (BMDB) are: two acquisition sessions, several sensors in certain modalities, balanced gender and age distributions, multimodal realistic scenarios with simple and quick tasks per modality, cross-European diversity, availability of demographic data, and compatibility with other multimodal databases. The novel acquisition conditions of the BMDB allow us to perform new challenging research and evaluation of either monomodal or multimodal biometric systems, as in the recent BioSecure Multimodal Evaluation campaign. A description of this campaign including baseline results of individual modalities from the new database is also given. The database is expected to be available for research purposes through the BioSecure Association during 2008.