The purpose of the present study was to examine the effects of an acute dose of a multi-ingredient pre-workout supplement on 5-km running performance and subjective measures of fatigue. Twenty aerobically-trained, males (n = 10, mean ± SD = 80.8 ± 6.1 kg) and females (n = 10, 64.5 ± 6.6 kg) completed two 5-km running races for time in a double-blind, cross-over fashion. During the first session, subjects were randomly assigned to ingest the supplement or placebo 30 minutes prior to running a 5-km race. The supplement contained multiple ingredients including caffeine anhydrous (150 mg), beta alanine (1.6 g), and arginine alpha-ketoglutarate (AKG) (1.0 g). Subjects also completed a 5-point Likert scale (1 = low, 5 = high) questionnaire to determine feelings of fatigue immediately prior to ingesting the substance (baseline), 30 minutes post-ingestion (immediately pre-race), and 5 minutes post-race. For the second session, subjects ingested the opposite substance (supplement or placebo) and underwent the same testing procedures (including time of day) as the first session. The results indicated there was no significant (p > 0.05) difference in 5-km race time between the supplement (23.62 ± 2.08 min) and placebo (23.51 ± 1.97 min) conditions. For the feelings of fatigue, there were no significant condition x time interactions or main effects for condition, but there were main effects for time. These findings indicated that the pre-workout supplement provided no ergogenic effect on 5-km race time or subjective feelings of fatigue when administered on an acute basis in aerobically-trained individuals.
Objective The purpose of this double blind, randomized, study was to determine the effects of Longvida® Optimized Curcumin on time trial performance time as well as the inflammatory mediator C‐reactive protein (CRP) after 2 weeks of an intensified training program. Methods Healthy men and women (aged 18–40 y) were randomly assigned to placebo (PLA; n=11), Curcumin 1 (LV1; n=12) or Curcumin 2 (LV2; n=11) groups. Participants consumed capsules of rice flour placebo (1000mg/day) or curcumin (1000mg/day; Longvida 1 (LV1) or 1000mg/day Longvida 2 (LV2)) for 14 days, during a 2‐week intensified, cycle training period, which consisted of 3 training sessions per week. Each training session consisted of 6, 90 second stationary cycling sprints at 80–90% heart rate max (HRmax) followed by 180 seconds of low intensity cycling at 50–60% HRmax. Age, body mass index (BMI), percent body fat (BF%; BodPod, Cosmed, USA), and peak oxygen uptake (VO2peak) were assessed at the pre intervention time point (PRE). Time trial performance (16.1 km; TT) was obtained on a stationary cycle and resting and fasted serum was evaluated for CRP using an enzyme‐linked immunosorbent assay at both PRE and post intervention (POST) time points. Differences among groups were assessed using a one‐way ANOVA, and PRE and POST measurements among groups were assessed using a two‐way mixed model ANOVA. Data are presented as mean ± standard deviation with significance set at α=0.05. Results At PRE, there were no significant differences between groups with respect to mean participant characteristics (age: 24.8±4.2 y; BMI: 24.0±3.5; BF%: 20.55±8.90; VO2peak 42.07±8.90 ml/kg/min). TT performance significantly improved an average of 1.41±5.01% (p=0.05) when PRE times were compared to POST. Additionally, although not statistically significant, the average TT time change from PRE to POST was −205.67 sec for PLA, −2.17 sec for LV1, −105.32 sec for LV2. There were no significant group effects or group by time interactions for CRP (PLA: 3.2 ±3.4 mg/L; LV1: 0.7 ±0.9 mg/L; LV2: 1.2±01.3 mg/L). Conclusions The intensified training period elicited a significant improvement in TT performance. When taken daily, the dose of curcumin used in this study did not appear to provide additional performance related benefits. However, when compared to the existing literature, the dose and the timing of curcumin intake as well as the mode of the activity may be related to curcumin‐mediated improvements in performance. Support or Funding Information Verdure Sciences, Noblesville, IN
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