Skull base osteomyelitis (SBO) also commonly known as malignant otitis externa was first described by Meltzer and Kelemen in 1959. Prior to the advent of the antibiotic era, this disease carried a poor prognosis with significant morbidity. It often proved fatal with mortality rates as high as 50%. Commonly seen in the immunocompromised patients, diabetes mellitus is an important associated comorbidity in the pathophysiologic development of this disease. Treatment is instituted by medical therapy with surgery having a limited role. Surgical intervention has a limited role, for example, in fungal SBO. Such cases may require local debridement and intraoperative tissue biopsies for histopathologic confirmation. This is to demonstrate fungal invasion into the skull base, as well as to exclude other sinister differential diagnoses like squamous cell carcinoma of temporal bone. In this case report, we present a rare case of candida SBO and the literature review.
Small cell neuroendocrine carcinoma (SCNEC) of the nasopharynx and nasal cavity is a rare condition. It is an aggressive malignancy with a high recurrence rate. Despite its rarity in the sinonasal region, it may occur as a second primary malignancy. Patients with cancer of the head and neck region are more prone to develop a second primary tumor due to the field cancerization phenomenon, and a higher incidence is seen in those who have previously received radiation therapy. A detailed clinical and histopathological examination is pivotal to diagnose SCNEC as a second primary malignancy. We wish to highlight such a peculiar case from our center.
Mucocele of the paranasal sinus is a cystic lesion with accumulation of mucus within the sinus walls, which is capable of expansion. The frontal sinus is most commonly involved, whereas ethmoidal, sphenoid, and maxillary mucoceles are rare. The floor of the frontal sinus is shared with the superior orbital wall, which explains orbital displacement in enlarging frontal mucoceles. This article presents a case of a spontaneous right frontoethmoidal mucocele with non-axial proptosis in a 26-year-old male patient who was referred by an ophthalmologist to our ENT (ear, nose, throat) clinic for a biopsy to rule out a sinonasal malignancy. An intranasal endoscopic approach was done to obtain a tissue biopsy in a clinic setting, which turned out to be a both diagnostic and therapeutic procedure with complete resolution of symptoms.
Concha bullosa (CB) is a pneumatised middle turbinate. Although CB is the most common variant of the middle turbinate, the formation of mucocele or mucopyocele of CB has been rarely reported. The inflamed mucosal lining of the concha bullosa may lead to mucocele formation. Infection of the retained secretion will later on lead to mucopyocele. We report a 12-year-old girl presented with right unilateral nasal blockage associated with rhinitis symptoms. She was initially diagnosed as nasal polyp which later on turned out to be a mucocele histpathologically.Bangladesh Journal of Medical Science Vol.17(4) 2018 p.691-693
Children eating behaviour was hypothesised as one of the factors associated with growth development as well as malnutrition among toddlers. This study aimed to explore the relationship between child eating behaviour among toddlers aged two to four years old and their respective Body Mass Index (BMI) or BMI for Age Z (BAZ). A cross-sectional study was conducted among parents and caregivers with toddlers between two to four years old, in the Klang Valley. The validated Children’s Eating Behaviour Questionnaire (CEBQ) was used to measure their child eating habit and behaviours. A total of 96 parents or caregivers of toddlers participated. Girls had lower BAZ than boys (-1.20 vs -0.15, p=0.030), and significantly higher satiety responsiveness and food fussiness scores (3.14 vs 2.80, p=0.005 and 2.83 vs 2.44, p=0.005 respectively). Emotional overeating had opposite effects on BMI and BAZ between genders. In this study, girls aged two to four year old had lower BMI and BAZ than boys; and demonstrated higher food avoidance behaviour. Emotional overeating is associated with opposite effects on BMI and BAZ between boys and girls. Among all toddlers, satiety responsiveness and food fussiness were associated with lower BAZ.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.