Introduction: The end product of purine metabolism in humans is uric acid (UA). Although uric acid can function as either an antioxidant or an oxidant depending on the surrounding environment, the chemical environment can also impact uric acid.The uric acid level in the serum can predict the development of diabetic nephropathy in type 1 diabetes. Objective: This study aims to determine factors that are perhaps having an association with acid uric. Method: Variables selection is basedon clinical importance. The most significant variable will be assigned and analyzed using Artificial Neural Network (ANN) through multilayer feed-forward and contour plot. Results: Through the architecture of MLFF with two hidden layers, it was found that Creatinine level, Urea level, Systolic Blood Pressure reading, Waist circumference reading, Gender play an essential role toward uric level with an accuracy of 97.7% and the predicted mean squared error (MSE.net) is 0.005. The combination of the selected variable showing the highest significance in predicting the level of uric acid. Conclusion: These findings offer useful future management action plans for patients with diabetes.By controlling these four variables can improve the level of health among diabetic patients. Bangladesh Journal of Medical Science Vol.20(4) 2021 p.741-747
Hypertension is one of the important public health challenges worldwide because of its high frequency and concomitant risks of cardiovascular and kidney disease. A hypertension model is built to test the interaction and significance between the factors. In this present paper, we present the results that gained from multiple logistic regression method and used to model the relationship between the ordinal outcome variable. The significant variables is chosen based on the p-value associated to the significant level of model that lies on α = 0.05. Logit determination and the correlation between the variables are also discussed for further analysis. there are three factors that most significant of the six factors tested were identified as having influence significantly the performance of human blood pressure (hypertension). These factors are age (p-value <0.000), body mass index (p-value <0.001) and systolic (p-value <0.001). The use of mathematical software PASW version 18 is applied in this research as an alternatives calculation procedures derived from the methodology.
Research on modeling is becoming popular nowadays, there are several of analyses used in research for modeling and one of them is known as applied multiple linear regressions (MLR). To obtain a bootstrap, robust and fuzzy multiple linear regressions, an experienced researchers should be aware the correct method of statistical analysis in order to get a better improved result. The main idea of bootstrapping is to approximate the entire sampling distribution of some estimator. To achieve this is by resampling from our original sample. In this paper, we emphasized on combining and modeling using bootstrapping, robust and fuzzy regression methodology. An algorithm for combining method is given by SAS language. We also provided some technical example of application of method discussed by using SAS computer software. The visualizing output of the analysis is discussed in detail.
Response surface methodology (RSM) can be used when the response variable, y, is influenced by several variables, x's. When treatments take the form of quantitative values, then the true relationship between response variables and independent variables might be known. Examples are given in SAS.
Introduction. Triglycerides are lipids composed of fatty acids that provide energy to the cell. These compounds are delivered to the body’s cells via lipoproteins found in the bloodstream. Increased blood triglyceride levels have been associated with high-fat or high-carbohydrate diets. Generally, increased triglyceride levels occur in conjunction with other symptoms that are difficult to notice and recognize. Objectives. The study’s goal was to develop and predict the model that could be used to explain the relationship between triglycerides and waist circumference, high-density lipoprotein (HDL), and hypertension status by determining the relationship between triglycerides and waist circumference, HDL, and hypertension status. This model was developed using qualitative predictor variables and incorporated data bootstrapping multilayer perceptron neural networks and fuzzy linear regression. Materials and procedures. This was a public health study that combined retrospective data analysis with methodology development. The medical records of patients who attended outpatient clinics at Hospital Universiti Sains Malaysia (USM) were collected and analyzed. This was to provide a more extensive illustration of the methods developed. Screening and selection of patient data were necessary following the inclusion and exclusion criteria. The patient’s medical record was used to obtain triglycerides, high-density lipoprotein (HDL), waist circumference, and hypertension status. Due to the critical nature of the variable, it was chosen to aid the clinical expert. The R-Studio software was used to develop the associated syntax for the hybrid model, which would define the association between the examined variables. The purpose of this study is to create a technique for the clinical trial design that utilizes bootstrapping, Qualitative Predictor Variables (QPV), Multiple Linear Regression (MLR), Artificial Neural Networks (ANNs), and Fuzzy Regression (FR). All analyses were performed using the newly introduced R syntax. The research developed a fuzzy linear model that increased modelling performance by incorporating clinically significant factors and validated variables via Multilayer Perceptron (MLP). Conclusion. The proposed technique for modelling and prediction appeared to be the ideal combination of bootstrap, Multilayer Feed Forward (MLFF) neural network, and fuzzy linear regression. The created syntax is currently being evaluated and validated clinically. For modelling and prediction, the proposed technique looked to be the best, as it incorporated bootstrap, MLFF neural network, and fuzzy linear regression. The established syntax is now being utilized in the clinic to evaluate and validate the outcome. In terms of variable selection, modelling, and model validation, this strategy was superior to earlier approaches for fuzzy regression modelling.
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