Hyponatremia in panhypopituitarism is multifactorial, it can be explained by the corticotropic deficit observed in pituitary insufficiency which is responsible for a lifting of inhibition on the anti-diuretic hormone with a consequent net reduction of water excretion, Hypothyroidism is also cited as a contributing mechanism for the development of acute hyponatremia in pituitary insufficiency through reduced free water excretion. Hyponatremia as a mode of revelation remains rare, we report a case of severe hyponatremia revealing pituitary insufficiency on pituitary macroadenoma.
Aggressive macroprolactinomas represent 0.4 to 4% of pituitary adenomas, they are more frequent in men, the positive diagnosis is easy, the evaluation of aggressiveness is essentially based on MRI and The treatment with dopaminergic agonist in first intention is now well established and should not be deferred apart from neurological emergency situations.
Introduction: Cardiac autonomic neuropathy (CAN) is one of the first complications of type 2 diabetes (T2DM) and a silent cause of cardiovascular morbidity and mortality. SUDOSCAN, a digital chronoamperometric analysis device, has appeared in recent years and allows a rapid and non-invasive quantitative assessment of sudomotor function, which will allow the measurement of sympathetic cholinergic function in the assessment of CAN by reflecting the state of the autonomic nervous system. The main purpose of the present study is to evaluate the usefulness of SUDOSCAN in the detection of cardiac autonomic neuropathy in type 2 diabetic patients. Patients and methods: In this study we recruited 85 patients with type 2 diabetes. The study data were collected by questionnaire, clinical examination and SUDOSCAN. Results: The 85 patients had a mean age of 58.32 ± 10.89 years, with a large female predominance, and a sex ratio of 0.28. 67% of our patients had diabetes for less than 10 years. The SUDOSCAN measurement noted 54.1% with a moderate risk of having CAN, 45.9% with a low risk, and a zero percentage with a high risk of having CAN. Conclusion: The risk score for cardiac autonomic neuropathy assessed by SUDOSCAN, and its ease of use and interpretation, make it a good screening test for cardiac autonomic neuropathy in patients with type 2 diabetes.
Introduction:Despitebeing exempt, manyDiabeticMuslims observe fastingduring the month of Ramadan. Wecarried out thiswork to study the impact of this practice Lean body mass in this group of patients. Material and methods:Westudied 176 MoroccanMuslimwith type 2 diabetes. The study data werecollectedthrough a questionnaire, clinicalexamination and bioelectricalimpedancemetry. The study variables were:weight, height, body mass index (BMI), lean mass, body fat and visceral fat. Results:All patients whofasted the entiremonth of Ramadan and who met the study monitoring deadlines have been included. The averageagewas 57 years +/- 11 years; 79% werewomen. Despite a similar BMI, therewas a reduction in weight (before: 76.85kg +/- 12.8 against 76.21kg +/- 12.8; p = 0.019), from body fat (before: 28.43kg +/- 9.3 against 26.72kg +/- 8.3; p = 0.015) and visceral fat (before: 10.41 +/- 3.36 against 9.95kg +/- 3.2; p = 0.007). Lean body mass has not changed, but stratification by sexshowed a significantincrease in women (before: 44.15 +/- 5.7 against 44.71kg +/- 5.7; p = 0.043). Conclusion:Ramadan fasting can bepracticed in all safetywithprior patient education and adjustmenttherapeutic. It alsoconfers an improvement in the body composition, especially in women.
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