Boricacid (BO3H3) is an inexpensive, efficient and mild catalyst for the synthesis of 2,4,5-triaryl-1H-imidazoles in excellent yields from the one-pot three-component condensation of benzil/ benzoin, an aldehydes and ammonium acetatein aqueous media under ultrasound at room temperature. The remarkable advantages offered by this method are green catalyst, mild reaction conditions, simple procedures, much faster reactions and excellent yield of products.
The Schiff bases derived from Salicylaldehyde with substituted amines and alpha benzoin oxime as a primary ligand are prepared by mixed with Cobalt (II), Nickel(II) and Copper (II). Structure have been proposed from elemental examination, like IR, NMR, thermal examination and magnetic susceptibility, Spectroscopic studies suggests that coordination occurs through azomethine nitrogen, hydroxyl group and oxime of the ligand to the metal ions. Elemental analysis of Schiff bases, alpha benzoin oxime and metal complexes are confirmed to stoichiometry of the type ML1L2 where Metals are Cobalt (II) andNickel (II) L1 are Schiff bases and L2 are alpha benzoin oxime. The mixed ligand Co(II) complexes were synthesize by using α-benzoin oxime as a primary ligand and Schiff base prepared from salicylaldehyde and chloroanilines with hydroxyanilines as a secondary ligand. The metal complexes have been characterized different elemental analyses and various chemical techniques such as molar conductance, magnetic susceptibility, infrared, NMR, spectral studies and thermal analysis. The elemental analysis data is consistent with their general formulation as mixed ligand complexes MLL’.xH2O. The bondings and structures of the complexes are discussed in detail on the basis of the results of various chemical studies. All of these metal complexes and ligands have been screened for their biological activities against selected pathogenic microbial strains. The Ditch Plate Method has been used to study the antibacterial activity against E. coli, S. typhi, S. aureusandS. pyogenes.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.