Hereditary coagulopathies characterized by reduced blood clotting occupy a special place among diseases of the blood system. The most common of these are hemophilia and Willebrand's disease. Hemophilia-the disease of "royals" - is an old, but still relevant disease. Hereditary coagulopathies, characterized by reduced blood clotting, occupy a special place among diseases of the blood system. Based on who data and the likely frequency of research on these diseases, the prevalence of hemophilia ranges from 3 to 25 patients per 10,000 population. Few studies of the oral cavity in patients with hemophilia have shown a high level of dental diseases, poor hygiene of the oral cavity. This is due to the lack of proper oral care, and dispensary monitoring, fear of prolonged bleeding after dental manipulations. For this reason, dentists try to avoid treating dental diseases in this category of patients. At the same time, modern achievements of medical science in the field of Hematology and the development of effective replacement therapy allow to prevent almost all types of bleeding. However, this group of patients is still unable to receive timely and high-quality dental treatment and prevention, which largely determines the high prevalence of inflammatory diseases of the maxillofacial region. All of the above is evidence of the presence of many predisposing factors of damage to the dental system in patients with hemophilia, as well as the need for preventive, therapeutic, including orthopedic dental measures for this category of patients.
Respublikada azot-fosfor-kaliy va ammoniy ekotoksikantlarning manbalari turli xil ammoniy va nitrat selitrlarni ishlab chiqaradigan "Samarqandkimyo" AJ tomonidan ishlab chiqarilgan. O'zbekistonda fosfat ishlab chiqarish azot-fosfor-kaliy va ammoniy toksikantlarni shakllantirish manbalariga: superfosfatlar, hexaxlorbutadien, tri - va tetrakloretilen va boshqalar kiradi. Shaharning sanoat zonasida neft-kimyo majmuasi korxonalari, "Samarqandkimyo" AJ, O'zbekistonda eng samarali va keng qo'llaniladigan 2,4-D guruhi azot va fosforli o'g'itlar ishlab chiqaruvchi yirik korxonalardan biri bo'lib, azot-fosfor-kaliy va ammoniy ksenobiyotiklarning asosiy yetkazib beruvchisi hisoblanadi.
Azot-fosforli selitrlarni ishlab chiqarish ko'plab tadqiqotchilar tomonidan barcha tirik organizmlarga juda kam dozalarda biologik ta'sir ko'rsatadigan keng miqyosli global superekotoksikantlar tomonidan e'tirof etilgan dioksinlarning hosil bo'lishi bilan birga keladi. Dioksinlar atrof-muhitga kümülatiya tufayli chidamli bo'lib, tanaga kirishning keng ehtimoli bilan ajralib turadi va shuning uchun odamlar uchun juda xavflidir. Hozirgi vaqtda "Samarqandkimyo"AJ tarkibiga kiruvchi ammiak va nitrat selitra (ammofos, nitrofos) ning 101 ishchi ishlab chiqarilishi tekshirildi. Ishlab chiqarishdagi ishchilarning yoshi 20 dan 55 yilgacha, shu jumladan erkaklar - 53 kishi, ayollar - 48, ushbu sohalarda ish tajribasi 1 dan 35 yilgacha bo'lgan.
Nazorat guruhi sifatida asosiy guruh bilan yoshi va jinsi bo'yicha bir xil bo'lgan, ammo zararli moddalar bilan, shu jumladan azot-fosfor-kaliy va ammoniy birikmalar bilan professional aloqaga ega bo'lmagan Samarqand viloyat stomatologiya poliklinikasiga stomatologik yordam so'rab murojaat qilgan 100 kishidan iborat ishlab chiqarish guruhi tekshirildi.
The authors conducted a comparative analytical description of the classification (ICD-10) of periodontitis and periapical tooth tissues. The terms “apical periodontitis”, “destructive periodontitis”, traditionally used in the formulation of the diagnosis, do not reflect the pathology of the affected tissue. Mistakes made in the diagnosis using the above terms lead to an incorrect formulation of the diagnosis and the choice of treatment tactics.
The obtained results led to the conclusion that the correct diagnosis of inflammatory and destructive diseases of the periapical tissues will significantly reduce the incidence of complications and increase the effectiveness of the treatment of periodontitis and diseases of the periapical tissues of the tooth.
The results of a comprehensive study showed that a high percentage of diagnostic errors is associated with confusion in terminology. The terms “apical periodontitis”, “destructive periodontitis”, traditionally used in the formulation of the diagnosis, do not reflect the pathology of the affected tissue.
The article discusses the development and application of technical devices for medical research. Biomedical engineering is one of the scientific and technical fields that explores and develops the application of engineering principles and concepts in medicine and biology to create artificial organs that can compensate for the lack of physiological functions. Medical engineering combines engineering and design skills with problem solubilities in the field of medicine and life sciences, and can also improve therapies based on the fundamental principles of molecular and cell biology, including diagnosis, monitoring and treatment.
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