Evidence is presented that considerable asymmetric induction can occur in Diels-Alder reactions catalysed by chiral alkoxyaluminium dichlorides.

The cytotoxic activities of optically pure and racemic steganacin congeners and analogues against KB cells in culture and the inhibitor activity of cilia regeneration in Tetrahymena were studied with regard to absolute and relative configurations. The stereochemical requirements of dibenzocyclooctadiene lignan lactones for activity were clarified.

No abstract

No abstract

No abstract