Background Full thickness skin grafts (FTSGs), although ideal for resurfacing large defects of the distal extremities in veterinary patients, have a high failure rate due to issues of adherence, infection and inadequate revascularisation because of its thickness and high nutritional demand. This study investigated the effect of Nigeria bee honey on FTSG take at the distal extremities of dogs. The study was conducted on 6 adult male Nigerian indigenous dogs using 3 of the 4 limbs of each dog randomly divided into 3 treatment groups: Nigerian bee honey (HON group), platelet-rich plasma (PRP group) and normal saline (CON group). Full‐thickness skin wounds (3 cm × 1.5 cm) were created on the lateral aspect of the radioulnar or metatarsal areas and dressed till adequate granulation tissues formed. Donor skins harvested from the lateral thorax of each dog were sutured to the recipient bed following application of the assigned treatment, and evaluated grossly and histologically on days 0, 4, 7, 10, 14, 17, and 21. Results A higher percentage (4/6 representing 66.7%) of complete graft take was observed in the HON and PRP groups as compared to 3/6 (50%) in the CON group. The HON group had a greater percentage (5/6 representing 83.3%) of adhered grafts as compared to the PRP (4/6 representing 66.7%) and CON (3/6 representing 50%) groups at day 4. There was a significant decrease (p = 0.022) in percentage necrosis between the CON and HON/PRP groups on day 10, 14 and 17. The percentage open mesh area for the HON group was significantly lesser at day 4, 7 and 10 when compared with CON (p < 0.001) and at day 4 when compared with PRP (p = 0.001). At histology, graft neovascularisation score was highest in the HON group on days 4, 14 and 21. Conclusion Nigeria bee honey enhanced take of meshed full-thickness skin autografts by promoting adherence to the recipient bed, enhancing fibroblast proliferation and collagen laydown, and accelerating the rate of neovascularisation suggesting promising application as an alternative modality to enhance FTSG take.
Gastric and intestinal ulceration with or without perforation poses a global health challenge in both human and animal populations. In animal species, it is often associated with patients presenting with hematemesis, abdominal pain, melena and anorexia, with erratic vomiting. The definitive diagnoses with imaging modalities are less feasible in poor resource settings due to lack of adequate facilities. This study investigated the prevalence and associated factors of gastric and intestinal ulcers in companion and exotic animal patients presented at the Veterinary Teaching Hospital, University of Ibadan, Nigeria, between 2009 and 2019 using hospital case records. Thirty-six cases of gastric and intestinal ulcer were recorded. They were mostly in canine (80.55%), few in exotic species [2 monkeys (5.55%), 1 lion (2.78%), 1 gazelle (2.78%), 1 dwarf crocodile (2.78%) and 1 fox (2.78%)] and one in an unspecified species (2.78%). Females (47.22%) and older animals (>1 year/69.45%) had higher occurrence than males (38.89%) and younger animals (<1 year/19.44%). All the patients were diagnosed with different pre-existing systemic conditions including: leptospirosis (19 cases/52.78%), chronic malnutrition (7 cases/19.44%), ehrlichiosis (2 cases/5.56%), trypanosomosis (2 cases/5.56%), babesiosis (2 cases/5.56%), hepatic tumor (1 case/2.78%), infectious canine hepatitis (1 case/2.78%), canine acute renal failure (1 case/2.78%) and granulomatous pneumonia (1 case/2.78%). There is therefore need to institute gastric and intestinal ulcer preventive and curative measures while treating predisposing primary disease conditions.
Background Cryptorchidism in dogs is of clinical concern due to its association with development of Sertoli cell tumours, seminomas and spermatic cord torsion. A patent inguinal ring has been found as a risk factor for peritoneal content migration and inguinal hernias. This study reports a case of bowel migration through a patent inguinal ring in a bilaterally cryptorchid dog and incarceration within the vaginal tunic of the left testicle. Case presentation A three-and-a-half-year-old bilaterally cryptorchid Lhasa Apso with a history of anorexia, vomiting, stranguria and inability to defecate was diagnosed with bowel incarceration in the vaginal tunic of a retained left testicle. Surgery performed under epidural anaesthesia with acepromazine/butorphanol premedication revealed a loop of the colon entrapped in the vaginal tunic of the retained left testicle. The incarcerated bowel was thoroughly examined for viability and repositioned into the abdominal cavity. The inguinal ring was repaired and bilateral cryptorchidectomy performed. Conclusion Cryptorchidectomy in dogs is often considered when there is concern for neoplasm or torsion of retained testes. However, this report suggests that cryptorchidectomy should be considered also to preclude the possibility of bowel obstructive emergencies.
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