Formula A (i.e., 0.33 g/100 mL of cold galactomannans) was effective in reducing certain pH-monitoring indices of uncomplicated GER, increased body weight and was well-tolerated by infants.
With the rise of the obesity epidemic in recent decades, non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease, not only in adults but in children as well. At present, the gold standard in diagnosing pediatric NAFLD is liver biopsyan invasive procedure associated with potentially severe complications. Therefore, the current efforts are directed towards the development of new non-invasive and accessible methods for the early diagnosis of NAFLD. Among the potential biomarkers are the micro-ribonucleic acids (miRNAs) -small molecules made up of 20-25 nucleotides, which exert their biological effect as regulators of protein synthesis. The aim of the present article is to provide a short description of miRNA function in hepatic metabolism and their possible use in diagnosing pediatric NAFLD.
This short review presents the definition of celiac disease (CD) and its epidemiology. The diagnostic tools are presented as well as the ESPGHAN 2019 guidelines for diagnosing CD.
РЕЗЮМЕВ краткия обзор е представено определението за целиакия, изложена е честотата на засягане, представени са "инструментите" за диагностиката й. Изложени са препоръките за диагностика на ESPGHAN 2019 г.
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