Background
Overactive bladder is a common syndrome that significantly affects the quality of life. Fibromyalgia is characterized by widespread pain, impacting patients' lives. The exact mechanisms of the two syndromes remain unknown, but there is an overlap between the suspected pathophysiologies.
Objective
To present an overview of the current research on the association between overactive bladder (OAB) and fibromyalgia.
Search strategy
A systematic search of four electronic databases was conducted.
Search strategy
Studies examining the correlation between OAB and fibromyalgia with female patients aged over 18 years were included.
Data collection and analysis
Two reviewers screened the studies for eligibility. Eligible studies were screened for quality. A meta‐analysis was performed for eligible studies.
Main results
Seven studies were included in the final review, of which six presented a positive association between the syndromes. The studies demonstrated a positive association between fibromyalgia and the severity of OAB and an adverse effect on the quality of life related to OAB. A mean effect size of 1.96 (95% confidence interval 0.85–3.06) was calculated.
Conclusion
OAB and fibromyalgia are both complex and multifactorial syndromes. The study presents an association between them, but additional studies on the topic should be conducted for a more precise conclusion.
Background: As the population ages emergency surgeries among the elderly population, including colonic resections, is also increasing. Data regarding the short- and long-term outcomes in this population is scarce. Methods: A retrospective study was performed to investigate mortality and mortality risk factors associated with emergent colectomies in older compared to younger patients in a single university affiliated tertiary hospital. Patients with metastatic disease, colectomy due to trauma or index colectomy within 30 days prior to emergent surgery were excluded. Results: Operative outcomes compared among age groups, included 30-day mortality, mortality risk-factors and long-term survival. 613 eligible patients were included in the cohort. Mean age was 69.4 years, 45.1% were female. Patients were divided into four age groups: 18–59, 60–69, 70–79 and ≥80-years. Thirty-day mortality rates were 3.2%, 11%, 29.3% and 37.8%, respectively and 22% for the entire cohort. Risk-factors for perioperative death in the younger group were related to severity of ASA score and WBC count. In groups 60–69, 70–79, main risk-factors were ADL dependency and ASA score. In the ≥80 group, risk-factors affecting perioperative mortality, included ASA score, pre-operative albumin, creatinine, WBC levels, cancer etiology, ADL dependency, and dementia. Long-term survival differed significantly between age groups. Conclusion: Perioperative mortality with emergency colectomy increases with patients’ age. Patients older than eighty-years undergoing urgent colectomies have extremely high mortality rates, leading to a huge burden on medical services. Evaluating risk-factors for mortality and pre-operative discussion with patients and families is important. Screening the elderly population for colonic pathologies can result in early diagnosis potentially leading to elective surgeries with decreased mortality.
Objectives: To evaluate the risk of sensorineural hearing loss (SNHL)
after mastoidectomy in patients with acute mastoiditis (AM) and compare
patients who received surgical versus conservative treatment. Methods: A
retrospective cohort study of medical records of all patients who were
diagnosed with AM at Soroka medical center between the years 2005-2020
and had an available hearing test. Data included demographics, clinical
characteristic, comorbidities, and a pure tune audiometry conducted in
our institution after recovery. Hearing loss (HL) was defined as a
decrease of 15 dB or more in a given frequency. HL was categorized as
mild (25-40 dB decrease), moderate (41-70) or severe (71db<).
Frequencies range was categorized as Low (<500 Hz), middle
(501-2000 HZ) or high (>2001) pitch. We divided the
patients to two groups; patients who received conservative treatment and
patients who underwent surgery. Results: A total of 24 patients met the
inclusion/exclusion criteria, 12 underwent surgery (mean age 20.2 m) and
12 received conservative treatment (mean age 20.1 m). A definite CHL of
10 to 20 dB could be diagnosed in 3 of the 5 patients in each group, who
had bone conduction thresholds measured. SNHL was not observed in any of
the patients old enough to have bone conduction tested Conclusions: This
is the first study to examine HL of children following AM. From our
limited study it seems that the disease itself as well as mastoidectomy
is not a risk factor for developing SNHL later in life.
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