Financial Disclosure Rachel G. Sinkey reports money was paid to her institution from GestVision and ProLab. Alan T. Tita reports money was paid to his institution from the NIH, CDC, and Pfizer for COVID-19 and RSV vaccine in pregnancy studies. Ashley N. Battarbee reports money was paid to her institution from the NIH and CDC for COVID-19 in pregnancy studies. Akila Subramaniam reports money was paid to her institution from the NIH. Jeff M. Szychowski reports money was paid to his institution from the NIH. Jodie Dionne-Odom currently receives grant funding from NIH/NICHD for an unrelated study on infection in pregnancy. Sixto M. Leal Jr. reports money was paid to his institution from the NIH, CDC, ADPH, CNINE, GenMark, mFluiDx, IMMY, SpeeDx, Abnova, Amplyx, IHMA, and JMI. Nitin Arora reports money was paid to his institution from the Congenital and Perinatal Infections Consortium,

Two years into the coronavirus disease 2019 (COVID-19) pandemic, we have now seen three main variant waves. We performed a retrospective cohort study of all pregnant patients with COVID-19 at our institution from March 22, 2020, to February 26, 2022, to evaluate disease severity and perinatal outcomes among the variants. Patients were