Objective: This study was conducted to evaluate the prophylactic antibiotic administration in the surgical clinic of Dr. H. Marzoeki Mahdi Hospital, Bogor, Indonesia. Methods:The data were assessed from the medical records of all patients who underwent surgery from January to December 2013 retrospectively. Antibiotic prophylaxis was assessed based on the Scottish Intercollegiate Guidelines and the National Guidelines of Antibiotic Usage, which includes the type, time, and duration of prophylactic administration of antibiotics.Results: A total of 577 patients were included in this study, consisting of 202 men and 375 women. The most frequently performed surgery is a common surgery 347 (60.1%), followed by obstetric operations 176 (30.5%), and orthopedic surgery 54 (9.4%). In this study, all patients received prophylactic antibiotics before surgery. Cefotaxime (87.8%) was the most commonly used antibiotics for surgical prophylaxis. Of the 577 patients, only 1.1% of patients reported with surgical site infection (SSI). Conclusion:This study shows that adherence to the guidelines of surgical antibiotic prophylaxis is still very low. Therefore, efforts should be made to increase the compliance of using antibiotic prophylaxis in accordance with standard guidelines to improve the rational use of antibiotics.
Background: Diarrhea is characterized by an increase in the frequency of bowel movements more than three times a day. This disease has a fairly high incidence rate in Indonesia, especially in children. One of the causes of diarrhea is a bacterial infection, therefore it needs to be treated with antibiotics. Several studies show that there are still many antibiotics that are used irrationally. It is necessary to analyze the rationality of the use of antibiotics in pediatric patients with diarrhea using the Gyssens method Objectives: This study is to ascertain the profile of acute diarrhea pediatric patients characteristic and evaluate antibiotics rationality with Gyssens method. Moreover, the purpose of this study is to analyze the factors that influence the rationality of the use of antibiotics in the inpatient pediatric acute diarrhea installation of Fatmawati Hospital 2018-2019 period. Material and Methods: This study is descriptive observational research. The study design was cross-sectional with retrospective data collection which was analysed then qualitatively with the Gyssens flow method Results: The result showed 54,29% antibiotics usde appropriately and rational. The irrational use of antibiotics was 45.7%. The results of statistical analysis with chi-square show a significant relationship between the rationality of antibiotics and the type of antibiotic (ρ = 0.000 < 0.05) and multiple logistic regression analysis showed that the route of drug administration (ρ = 0.000 < 0.05) affected the rationality of antibiotics use. Conclusions: Less than 50% of the patients received irrational treatment according to the Gyssen flow chart and according to the results of statistical analysis, the type of antibiotic and the route of drug administration affected the rationality of antibiotics.
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