This randomized clinical trial examines a decision support tool that provides lower back pain information and self-management recommendations that are specific to an individual’s characteristics, symptoms, and symptom progression.
Case-Based Reasoning systems retrieve and reuse solutions for previously solved problems that have been encountered and remembered as cases. In some domains, particularly where the problem solving is a classification task, the retrieved solution can be reused directly. But for design tasks it is common for the retrieved solution to be regarded as an initial solution that should be refined to reflect the differences between the new and retrieved problems. The acquisition of adaptation knowledge to achieve this refinement can be demanding, despite the fact that the knowledge source of stored cases captures a substantial part of the problem-solving expertise. This paper describes an introspective learning approach where the case knowledge itself provides a source from which training data for the adaptation task can be assembled. Different learning algorithms are explored and the effect of the learned adaptations is demonstrated for a demanding component-based pharmaceutical design task, tablet formulation. The evaluation highlights the incremental nature of adaptation as a further reasoning step after nearest-neighbour retrieval. A new property-based classification to adapt symbolic values is proposed, and an ensemble of these property-based adaptation classifiers has been particularly successful for the most difficult of the symbolic adaptation tasks in tablet formulation.
The exponential increase in published articles makes a thorough and expedient review of literature increasingly challenging. This review delineated automated tools and platforms that employ artificial intelligence (AI) approaches and evaluated the reported benefits and challenges in using such methods. A search was conducted in 4 databases (Medline, Embase, CDSR, and Epistemonikos) up to April 2021 for systematic reviews and other related reviews implementing AI methods. To be included, the review must use any form of AI method, including machine learning, deep learning, neural network, or any other applications used to enable the full or semi-autonomous performance of one or more stages in the development of evidence synthesis. Twelve reviews were included, using nine different tools to implement 15 different AI methods. Eleven methods were used in the screening stages of the review (73%). The rest were divided: two in data extraction (13%) and two in risk of bias assessment (13%). The ambiguous benefits of the data extractions, combined with the reported advantages from 10 reviews, indicating that AI platforms have taken hold with varying success in evidence synthesis. However, the results are qualified by the reliance on the self-reporting of the review authors. Extensive human validation still appears required at this stage in implementing AI methods, though further evaluation is required to define the overall contribution of such platforms in enhancing efficiency and quality in evidence synthesis.
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