Background: Several sick neonates require transfer to tertiary level care neonatal unit for treatment. The facilities of neonatal transport in India are not optimal and the newborn thus transported can become hypothermic, hypoxic, and/or hypoglycemic which can affect the neonatal outcome. These parameters can be maintained during transport by adopting simple measures. Aim: Study impact of acute physiological parameters during transfer of neonates on their immediate outcome by using TOPS score. TOPS Score -temperature, oxygensaturation, perfusion (assessed by capillary refill time), blood Sugar. Materials and Methods: This prospective observational study was conducted at the special care newborn unit, Indore enrolling 513 transported neonates. TOPS scoring for each neonate was done at admission, and then the parameters of the TOPS score were correlated with the outcome at 48 h of admission. Results: A total of 513 transported newborns were assessed, 48.73% newborns were hypothermic, 33.91% had poor perfusion, 28.46% were hypoxemic, and 22.22% were hypoglycemic. Hypoxemia and hypoglycemia had the highest sensitivity (93.39% and 80.18%, respectively) while hypoglycemia had the highest specificity (92.87%). Conclusion: TOPS score is a useful and easy to use the method to assess the physiological status and predict early mortality in transported neonates.

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Background: Eclampsia is a major cause of perinatal mortality. There is a need for studies that will correlate maternal factors and perinatal outcome, which will provide potential strategies to improve fetal outcomes in pregnancies complicated by eclampsia. Aims and Objectives: This study aims to study perinatal outcome of babies born to mothers with antepartum eclampsia and to correlate outcomes with convulsion delivery interval. Materials and Methods: A study included 200 patients diagnosed and managed as antepartum eclampsia in the Department of Obstetrics and Gynaecology in MGM Medical College, Indore. A detailed pro forma was prepared and was filled with patient’s information, investigations, treatment, and birth details. The final outcome of both, the mother and her newborn, including stillbirths and early neonatal deaths was included in the study and the perinatal outcome was correlated with convulsion delivery interval. Results: Incidence of antepartum eclampsia in our study was 2.1%. About 86.4% of women lack regular antenatal care at health care center. Only 7% of women delivered within 6 h of onset of convulsion. Case fatality rate was found to be 13%. There were 59.5% premature deliveries. Perinatal mortality (stillbirth and early neonatal deaths) was 42.5%. Significant association was found between convulsion delivery interval and perinatal outcome (P<0.05). Furthermore, association between use of multiple antiepileptic agents and perinatal outcomes was statistically significant. Conclusion: Eclampsia being a major cause of perinatal mortality need early diagnosis, prompt referral from peripheral health centers, and timely intervention for improvising both perinatal and maternal outcomes.

Background: Late preterm babies born between 34 and <37 weeks of gestation have documented various short-term and longterm adverse outcomes, extra burden on health care, and increased hospitalization rate. Objective: The objective of this study was to evaluate the immediate outcome of late preterm neonates and to compare their morbidity and mortality with term neonates. Materials and Methods: A prospective observational study was conducted among late preterm babies and term babies from January 2015 to July 2016 in a hospital of Indore. A pre-structured pro forma was used to record data on antenatal care, maternal risk factors, mode of delivery, birth weight, gestational age, gender, diagnosis, relevant investigations, duration of stay, and outcome. Their mortality and morbidity pattern were compared with the term counterparts. Results: The total number of live births during the study period was 14,372, of which 2602 were late preterm neonates (16%). Neonatal intensive care unit admission rate was 24.7% among late preterm while 8.87% in term neonates. Jaundice (9%), septicemia (7.8%), respiratory distress (7.6%), and hypoglycemia (6%) were among the common morbidities in late preterm babies, while in term group the incidence rates of these complications were 3.34%, 3.38%, 3.41%, and 2.56%, respectively. Conclusion: The mortality and morbidity among late preterm neonates were higher as compared to their term counterparts, implying the need for special attention to these babies because they may be overlooked among other preterm and sick babies.