The utilization of antimicrobials is essential to battle bacterial ailment. Yet, because of the expanding abuse of antimicrobial medications that are utilized in the treatment of infectious diseases, resistance by bacteria developed. The objective of the investigation is to detect the in vitro antibacterial impact of bay leaf water concentrates utilizing distinctive extraction strategies. The impact of water concentrates of bay leaf ( Laurus noblis) employing maceration and decoction extraction methods against Staphylococcus aureus and Escherichia coli were tested by “agar well diffusion” technique. The consequences of the investigation demonstrated insignificant differences between techniques for extractions. The study concludes that the in vitro antibacterial effect might be potentiated against test strains by using different methods for extraction and solvent systems, which might be helpful to defeat antimicrobial resistance.
An increasing interest in the research and isolation of different flavonoids from plants due to their beneficial and potential therapeutic effects as reported in many literatures. Achillia santolina belongs to the family Astaraceae, is a known plants rich in flavonoids and other phytochemicals that exhibit many biological activities like cytotoxicity, anti-inflammatory, antimicrobial, cholesterol level reduction and anticancer activity. The plant total flavonoids had been extracted by reflux condenser apparatus with 10% aqueous HCl then aglycone moiety was obtained with ethyl acetate. Quantitatively, the extraction yield of ethyl acetate (EA) fraction was 0.7689gm/40 gm (1.922%) of dry plant materials.While the total flavonoid content was (22.01362±2.1mg/g) of Quercetin equivalent of dry extract. For quantitative estimation of individual aglycons, Luteolin showed the highest concentration in EA fraction followed by Apigenin, Isorhamnetin, Quercetin, and Kaempferol with concentrations of (0.223±0.17), (0.184±0.18), (0.151±0.14), (0.148±0.08), and (0.024±0.10) μg/mg of dry extract, respectively. The current study showed Achillia santolina grown in Iraq is a valuable plant and considered as a rich source of flavonoids for combating many diseases.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.