A rare case of SCFN was diagnosed in a newborn, a rare disease in the neonatal period, emphasizes the importance of a histological findings for a definitive diagnosis. Subcutaneous fat necrosis of the newborn (SCFN) is an uncommon panniculitis of neonates. Although SCFN is a self-limited condition, recognition of this entity is important, as affected infants require monitoring for associated hypercalcemia or other complications. SCFN generally has a good outcome, with spontaneous resolution of skin lesions over weeks to months. However, death from hypercalcemia has been reported in a few infants with SCFN.
Herein we are presenting unusual case of severe neutropenia and JIA in a child. To our understanding, in this particular case, maternal Covid-19 caused an unusual presentation of neutropenia and JIA, with very high ANF. The role of neutrophils in pediatric rheumatology is an understudied field but is receiving increasing attention. Although clearly implicated in JIA, the specific contribution of neutrophils to pathogenesis and the use of neutrophil activity as biomarkers require further study.
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