Ablative fractionated carbon dioxide (fCO 2 ) laser may be a useful tool to improve noticeable scars after skin cancer surgery. Therefore we evaluated 40 patients who have been treated with fCO 2 laser for facial scars after skin cancer surgery. This retrospective study is based on blinded evaluation of pre-and postoperative photographs. Patients (n = 40), laypersons (n = 5) and experts (n = 5) evaluated the esthetics and the Vancouver scar scale as primary endpoints. Secondary endpoints included patient satisfaction and treatment safety. Patients, laypersons and experts consistently assessed a significant improvement of scar quality and appearance after fCO 2 laser treatment, which was paralleled by high patient satisfaction. In conclusion, ablative fCO 2 laser is effective in improving noticeable postsurgical scars. Patients are highly satisfied with post-laser results.