Nilgün Karalı scite author profile

A series of 2/3/4-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)amino]benzenesulfonamides, obtained from substituted isatins and 2-, 3- or 4-aminobenzenesulfonamide, showed low nanomolar inhibitory activity against the tumor associated carbonic anhydrase (CA, EC 4.2.1.1) isoforms IX and XII - recently validated antitumor drug targets, being much less effective as inhibitors of the off-target cytosolic isoforms CA I and II.

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Synthesis and antitubercular activity of 4-(3-coumarinyl)-3-cyclohexyl-4-thiazolin-2-one benzylidenehydrazones

Karalı

Kocabalkanli

Gürsoy

et al. 2002

Il Farmaco

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Isatin analogs as novel inhibitors of Candida spp. β-carbonic anhydrase enzymes

Akdemir

Güzel-Akdemir

Karalı

et al. 2016

Bioorganic & Medicinal Chemistry

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Nilgün Karalı

Synthesis and structure–antituberculosis activity relationship of 1H-indole-2,3-dione derivatives

Synthesis of new spiroindolinones incorporating a benzothiazole moiety as antioxidant agents

Synthesis and antituberculosis activity of 5-methyl/trifluoromethoxy-1H-indole-2,3-dione 3-thiosemicarbazone derivatives

Synthesis and primary cytotoxicity evaluation of new 5-nitroindole-2,3-dione derivatives

Synthesis and primary cytotoxicity evaluation of 3-[[(3-phenyl-4(3H)-quinazolinone-2-yl)mercaptoacetyl]hydrazono]-1H-2-indolinones

Discovery of novel isatin-based sulfonamides with potent and selective inhibition of the tumor-associated carbonic anhydrase isoforms IX and XII

Synthesis and antitubercular activity of 4-(3-coumarinyl)-3-cyclohexyl-4-thiazolin-2-one benzylidenehydrazones

Isatin analogs as novel inhibitors of Candida spp. β-carbonic anhydrase enzymes

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