Background: The unpredictability of the progression of coronavirus disease 2019 (COVID-19) may be attributed to the low precision of the tools used to predict the prognosis of this disease. Objective: To identify the predictors associated with poor clinical outcomes in patients with COVID-19. Methods: Relevant articles from PubMed, Embase, Cochrane, and Web of Science were searched and extracted as of April 5, 2020. Data of interest were collected and evaluated for their compatibility for the meta-analysis. Cumulative calculations to determine the correlation and effect estimates were performed using the Z test. Results: In total, 19 papers recording 1,934 mild and 1,644 severe cases of COVID-19 were included. Based on the initial evaluation, 62 potential risk factors were identified for the meta-analysis. Several comorbidities, including chronic respiratory disease, cardiovascular disease, diabetes mellitus, and hypertension were observed more frequent among patients with severe COVID-19 than with the mild ones. Compared to the mild form, severe COVID-19 was associated with symptoms such as dyspnea, anorexia, fatigue, increased respiratory rate, and high systolic blood pressure. Lower levels of lymphocytes and hemoglobin; elevated levels of leukocytes, aspartate aminotransferase, alanine aminotransferase, blood creatinine, blood urea nitrogen, high-sensitivity troponin, creatine kinase, high-sensitivity C-reactive protein, interleukin 6, D-dimer, ferritin, lactate dehydrogenase, and procalcitonin; and a high erythrocyte sedimentation rate were also associated with severe COVID-19. Conclusion: More than 30 risk factors are associated with a higher risk of severe COVID-19. These may serve as useful baseline parameters in the development of prediction tools for COVID-19 prognosis.

Background: The unpredictability of the progression of coronavirus disease 2019 (COVID-19) may be attributed to the low precision of the tools used to predict the prognosis of this disease. Objective: To identify the predictors associated with poor clinical outcomes in patients with COVID-19. Methods: Relevant articles from PubMed, Embase, Cochrane, and Web of Science were searched as of April 5, 2020. The quality of the included papers was appraised using the Newcastle-Ottawa scale (NOS). Data of interest were collected and evaluated for their compatibility for the meta-analysis. Cumulative calculations to determine the correlation and effect estimates were performed using the Z test. Results: In total, 19 papers recording 1,934 mild and 1,644 severe cases of COVID-19 were included. Based on the initial evaluation, 62 potential risk factors were identified for the meta-analysis. Several comorbidities, including chronic respiratory disease, cardiovascular disease, diabetes mellitus, and hypertension were observed more frequent among patients with severe COVID-19 than with the mild ones. Compared to the mild form, severe COVID-19 was associated with symptoms such as dyspnea, anorexia, fatigue, increased respiratory rate, and high systolic blood pressure. Lower levels of lymphocytes and hemoglobin; elevated levels of leukocytes, aspartate aminotransferase, alanine aminotransferase, blood creatinine, blood urea nitrogen, high-sensitivity troponin, creatine kinase, high-sensitivity C-reactive protein, interleukin 6, D-dimer, ferritin, lactate dehydrogenase, and procalcitonin; and a high erythrocyte sedimentation rate were also associated with severe COVID-19. Conclusion: More than 30 risk factors are associated with a higher risk of severe COVID-19. These may serve as useful baseline parameters in the development of prediction tools for COVID-19 prognosis.

Introduction: Heart failure is a pathological condition in which the heart's organs no longer have the ability to pump blood to the ventricles and throughout the body. One of the leading causes of morbidity and mortality is heart failure. Functional capacity and patient quality of life are correlated in patients with heart failure. Exercise and diet can be used to increase functional capacity. This study aimed to identify the effectiveness of exercise and diet as treatment modalities to improve patient well-being and quality of life outcomes. Methods: This article employs the evidence-based practice of physical exercise (exercise) and a comprehensive diet for heart failure as part of a literature review methodology. Journal articles that meet the requirement of 12 were included in this article. While articles that are inappropriate or only abstract did not include in this study. Result: Twelve articles were included in the study. The suggested physical activity, such as walking, can be completed in 6 minutes or 30 minutes over a week, three times. And a 30-minute riding session is possible. The DASH diet is advised, and patients should receive the recommended amount of sodium (1500 mg/day). Conclusion: Physical exercise and a comprehensive diet that can be done well in heart failure patients can help patients reduce the risk of developing symptoms that can trigger the severity of heart failure. Moreover, patients can carry out daily activities and do their jobs well, and improve their quality of life.

Introduction: The coronavirus disease of 2019 (COVID-19) is a particularly hazardous virus due to its rapid transmission. The spread of COVID-19 is so rapid that the WHO has labeled it a pandemic, and Indonesia has declared it a national catastrophe. The purpose of this essay was to summarize the management of cancer patient care during the COVID-19 epidemic. Methods: In this review, we used the PRISMA method and article sources from databases, including Scopus, Science Direct, SAGE, and CINAHL/EBSCO, from the years 2019 to 2020.. Inclusion criteria include research conducted in human, using nursing management strategies in cancer patients, and article written inEnglish and have been published in 2020. Exclusion criteria include research on non-human, articles that did not mention cancer care management during the COVID-19 epidemic, review and survey studies. Result: This review looked at 14 articles from different nations. Two studies used phone massage as an intervention, three studies used a combination of phone massage and phone call with smartphone technology, five studies used a video call to monitor cancer care management, one study used email or social media to monitor cancer care management, and three studies used web applications that are connected to the internet. Conclusion: In conclusion, our findings suggest that continuing anticancer treatment during the COVID-19 pandemic is safe and possible if appropriate and stringent infection control measures are implemented. In the future, more extensive research of COVID-19 infection in cancer patients may aid in the care of oncology patients

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