Background: Plants having active constituents possess pharmaceutical use and nutritional values. Herbal medicine or food supplement is gaining popularity, as well as scientific research on wheatgrass as a “functional food”. Objective: The target behind accepting wheatgrass as a study for review is to have clinical and non-clinical investigations on the wheatgrass plant at an equivalent stage. To let individuals, think about different affirmed uses and activities of the plant. Methods: Plants having so many nutritional and therapeutic values have been selected for review so that consumers or patients could be benefitted from their therapeutic uses. Recently, the interests in the use of herbal products have grown dramatically in the western as well as developing countries. The review was extracted from searches performed on Google Scholars, Google Patents, etc. Data from sources have been collected and reported here at one place in order to provide further research on wheatgrass. Results : Wheatgrass is a high source of various vitamins and minerals; it possesses many activities like anti-oxidant, anti-inflammation, anti-bacterial and many more. Wheatgrass’ uses, benefits and properties non-clinical data and clinical studies has been thoroughly studied. Patents filed related to wheatgrass are mentioned here, so as to motivate other innovators to search for new activities or molecules. Conclusions: Wheatgrass can be used in pharmaceutical formulations and can be used as nutritional supplements due to its anti-oxidant nature, anti-microbial activity, anti-bacterial activity, anti-fungal activity. It is also called “Panacea on Earth” owing to its wide range of nutritive and medicinal aspects.
Background: Novel Drug Delivery Systems (NDDS) provide numerous benefits compared to conventional dosage forms. Poor aqueous solubility, low bioavailability, frequent dosing, and particular hydrophilic lipophilic character of the drug are the biological factors associated with the traditional systems leading to the development of SLNs. Objective: For improving the solubility profile, enhancing the bioavailability, and attaining the best possible therapeutic effect of lipid inclined or aqueous inclined drug; formulating solid lipid nanoparticles is the best choice. Methods: Solid Lipid Nanoparticles (SLNs) have been projected as a colloidal carrier system having a particle size of 50–1,000 nm, collectively combining the benefits of other colloidal systems like liposomes, emulsions etc. for delivering the drug at the target site. High absorption, high stability, and efficient drug packing enhance the pharmacokinetic and pharmacodynamics properties of the packed drug. Result: Solid Lipid Nanoparticles can be developed in different dosage forms and administered via routes such as nasal, rectal, oral, topical, vaginal, ocular, and parenteral. They have higher physicochemical stability and the batch size can be easily scaled up at low cost. Lipophilic as well as hydrophilic drugs can be easily incorporated in solid lipid nanoparticles. Conclusion: In this manuscript, the authors have reviewed different aspects of solid lipid nanoparticles, major principles behind mechanism methods; recent patents, applications, and therapeutic potentials of solid lipid nanoparticles.
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