Non-Hodgkin lymphomas constitute 1% of gastrointestinal system tumors. Lymphomas can occur from the oral cavity to the rectum. Primary gastrointestinal lymphomas are most frequent in the stomach, followed by the small and large intestines. Here, we report a 41-year-old male patient who had been under chemotherapy following a diagnosis of diffuse large B-cell lymphoma transformed from MALT lymphoma and discuss new treatment options. He presented to us with an acute abdomen. To our knowledge, this was the first case in the literature that presented with acute abdomen and was diagnosed as diffuse large B-cell lymphoma that transformed from MALT lymphoma. In addition, for the treatment, we want to draw attention to the importance of surgery, in addition to chemotherapy.Key Words: Maltoma, diffuse large B-cell lymphoma, acute abdomen, ileus ÖZET Non-Hodgkin Lenfomalar (NHL) gastrointestinal sistem (GİS) malin tümörlerinin %1'ini oluşturur. Lenfomalar GİS'in, oral kaviteden rektuma kadar her hangi bir yerinde oluşabilir. Primer gastrointestinal lenfomaların mideden sonra en sık görül-düğü alan ince ve kalın barsaklardır. Akut batın tablosu ile gelen MALT lenfomadan transforme olmuş diffuz büyük B hücreli lenfoma tanısı konularak kemoterapi başlanan 41 yaşındaki erkek hasta sunulmuş ve tedavi seçenekleri tartışılmıştır. Literatür-de akut batın tablosu ile gelen ve lenfoma tanısı konulan vakalar içinde MALT lenfomadan transforme olmuş diffuz B hücreli lenfoma tanısına rastlamadık. Ayrıca son yıllarda yapılan çalış-malarda vurgulanan kemoterapinin yanında cerrahinin önemine dikkat çekilmiştir.Anahtar Sözcükler: Maltoma, diffuz büyük B hüçreli lenfoma, akut batın, ileus
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