Recent work in the sociology of scientific knowledge leads us to believe that organization exists in the interpretive processes of its members. A theory of communication is presented which views the communicational process as a double translation, from text to conversation and conversation into text. Using this theory as a basis, a conception of complex and extended forms of organization is developed which demonstrates that the text-conversation cycle underlies a complex process of networking out of which the identity of the organization emerges, and social structuring occurs, resulting in the division of labor and coordination. Implications of the theory are briefly considered for research.

No abstract

This Topical Review summarizes some of the work we have done mainly in the cat using agonists and antagonists of various neurotransmitter systems injected intravenously or intrathecally to initiate or modulate the expression of hindlimb locomotion after a spinal lesion at T13. The effects of the same drugs are compared in various preparations: complete spinal, partial spinal or intact cats. This has revealed that there can be major differences in these effects. In turn, this suggests that although the locomotor rhythm might normally be triggered and modulated by the activation of a variety of receptors (noradrenaline, serotonin, glutamate), after spinalization there appears to be a predominance of glutamatergic mechanisms. Recent work also suggests that, in the cat, the integrity of the midlumbar segments is crucial for the expression of spinal locomotion. Taken together, this work raises some hope that a targeted pharmacotherapy with better understood drugs and mode and locus of delivery could become a clinical reality.

Pharmacological agents have been shown to be capable of inducing a pattern of rhythmic activity recorded in muscle nerves or motoneurons of paralyzed spinal cats that closely resembles the locomotor pattern seen in intact cats. Further work, using intraperitoneal or intrathecal injections, suggests that different neurotransmitters may be involved in various aspects of locomotor control, e.g., initiation and modulation of the pattern. Although precursors, agonists or the neurotransmitters themselves of several systems have been investigated (noradrenergic, dopaminergic, serotonergic, glutamatergic), the noradrenergic system seems the most efficient in triggering locomotion in complete spinal cats, with the alpha-2 agonists (clonidine, tizanidine, oxymetazoline) being more potent than the alpha-1 agonist, methoxamine. Moreover, the potency of the drugs may depend on the time of application after the spinal lesion. In chronic spinal cats capable of spontaneous walking on hindlimbs on the treadmill, all neurotransmitters appear to exert distinct recognizable effects on the locomotor pattern. More recent work also suggests that the effects of drugs may differ significantly depending on the type of spinal lesion. For instance, clonidine further reduces the level of weight support during quadrupedal locomotion of cats with lesions of the ventral-ventrolateral funiculi, possibly due to an interference of clonidine with essential compensatory mechanisms used by these animals to walk. Such considerations as the type of drugs, type of lesions, and the time after the lesion will be important for future studies in spinal cord injured patients.

This study uses a discursive perspective to analyze the way in which top managers legitimize change in official announcements. It focuses on the foundations of legitimacy invoked using both Weber's typology, based on modes of authority, and the conventionalist model, stressing the constitutive frameworks that justify collective action. We use a narrative approach to examine four texts intended for employees in the context of mergers-acquisitions in the Canadian financial services sector. We look at those announcements as wedding narratives. A framework based on the canonical schema and Greimas's actantial model was applied to the texts. The analysis reveals that these narrations of corporate marriages, while describing the same event, give distinct versions of it. These distinctions bring out differences between firms in terms of the foundations of legitimacy invoked, the contribution of the various actors, and the narrative style favoured.Communication's critical role in the implementation of change is often cited in the literature (Ford and Ford, 1995;Kanter, 1987). Communication is presented as a tool for diffusing top management intentions (Demers, 1993) and for preparing minds to a new context of action (Giroux and Taylor, 1995). Managers legitimate change to encourage employee commitment to imminent transformations (Armenakis et al., 1993).Mergers and acquisitions (M/As) are a formidable challenge for change management. The joined organizations are often radically transformed and