Background: Primary retroperitoneal tumors (PRT) are a group of extremely heterogeneous soft tissue tumors that grow in the retroperitoneal space and have no organic affiliation. Tumors usually become symptomatically late and cause secondary symptoms or become palpable once they have become significantly large. Preoperative diagnosis of PRT is essential for assessing subsequent treatment tactics, planning the approach and volume of surgery, by detecting the structural component, relationships with adjacent anatomical structures and the degree of invasion. Material and methods: Complex prospective and retrospective analysis of clinical, anamnestic and imaging data of 118 patients with primary and nonprimary retroperitoneal tumors, investigated and treated at the Institute of Oncology of the Republic of Moldova during 2015-2020. Results: To determine the primary PRT diagnosis for the clinician, it is primordial to rule out the organic or secondary nature of the tumor. Thus, the patients were examined by: abdominal USG – 118 patients (100%), abdominal and small pelvic contrast-enhanced CT – 118 patients (100%), MRI – 3 patients (2.5%), videoesogastroduodenoscopy – 32 patients (27.1%), videocolonoscopy – 31 patients (26.3%), irigography – 4 patients (3.4%), urography – 29 patients (24.6%). Conclusions: Contrast-enhanced CT provides more accurate data than USG. The image obtained at the USG examination is flat, therefore the dimensional measurements of the tumor are not always performed on the longest tumor axis, especially in the case of polylobulated or giant tumors, while the tomographic examination techniques allow the three-dimensional reconstruction of the tumor with more accurate assessment of the tumor size.
Background: Timely diagnosis of primary retroperitoneal tumours is one of the current challenges of clinical oncology. This is due to the rarity, polymorphism and diagnostic difficulties of primitive retroperitoneal tumours. Material and methods: The study is cross-sectional, prospective and retrospective. The study group is represented by 118 patients with abdominal and retroperitoneal space tumours. Using the receiver operating characteristic (ROC) analysis curve and calculating the average quality of the diagnostic model, the informativeness of ultrasonography in the diagnosis of primary retroperitoneal tumours (PRT) was appreciated. Results: For tumour localization, the ultrasonography (USG) as a diagnostic model demonstrated an appropriate use criteria (AUC) of 0.641 (95% CI 0.541, 0.740, p <0.001), and the mean quality of the diagnostic model was 0.54. Following the statistical analysis, was found a partial correlation between the size of the tumour and the dimensions estimated at USG of 0.540 (95% CI 0.295, 0.737, p <0.001), which represents a high positive correlation. To determine the uni- or multicentric character of the tumour, the USG demonstrated an integrative value of sensitivity and specificity of 0.644 (95% CI 0.415, 0.873, p <0.001. In assessing the proximity ratio of retroperitoneal tumours, the highest AUC was recorded in the assessment of the ratio of tumour to pancreas – 0.838 (95% CI 0.705.0.971, p <0.001) and kidney – 0.861 (95% CI 0.699, 1.024, p <0.001). Conclusions: Ultrasonography is a fairly informative imaging diagnostic method in the diagnosis of retroperitoneal tumours. The characteristics of the tumours obtained after the ultrasound examination provide indirect information about the malignant or benign nature of the primitive tumour, which allows the assessment of the next stages of diagnosis and treatment.
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