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749lymphocytes themselves are in some way affected by the presence of the cancer. I t remains unclear whether the lymph-nodes draining gastro-intestinal cancer behave in the same manner as those draining experimental animal tumours. Lymphocyte transformation indices in the nodes containing tumour metastases were similar to those which were free of tumour and it is not clear whether the lymph-node cells were sensitized by the tumour. I t will be of importance to test the response of these lymph-node lymphocytes to specific tumour antigens by the use of other techniques. In this way we may be able to determine precisely the role of lymph-nodes in the immunological control of gastrointestinal cancer.

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