Background Most recent laboratory studies have suggested a promising role of vitamin D and its analogs as novel chemotherapeutic agents for cancer treatment. However, epidemiological evidence, especially regarding the effects of vitamin D on gastric cancer is still inconsistent. Objectives Our research aimed to evaluate the associations between vitamin D intake and the risk of developing gastric cancer through a case-control study in North Vietnam. Methods We accessed databases of the previous completed case-control studies to derive 1182 incident gastric cancer cases and 2995 hospital controls selected from hospitals in Hanoi from 2003 to 2019. Vitamin D intake was computed by multiplying the food frequency intake with nutrient content based on the Viet Nam Food Composition Tables. Data were collected through face-to-face interviews by trained interviewers using the validated semi-quantitative food frequency and demographic lifestyle questionnaires. The odds ratio and 95% confidence interval (OR and 95%CI) were estimated using unconditional logistic regression analysis. Results We observed a continual decline in gastric cancer risk according to the level-up of vitamin D intake in both genders, men, and women [Fifth vs. bottom quintile, OR, 95%CI: 0.68 (0.53, 0.86), OR, 95%CI: 0.72 (0.53, 0.97), OR, 95%CI: 0.58 (0.38, 0.89), respectively. Per increment quintile, the statistically significant decreased risk was seen by 7% in men and 13% in women. The significant inverse association between vitamin D intake remained in the subgroups of ever and never tobacco smoking; negative and positive H. pylori infection. Conclusion The findings suggested that sufficient vitamin D intake was associated with a lower risk of Gastric Cancer in the Vietnamese population.
Aims: This study aimed to describe the characteristics of the workplace-related clusters of COVID-19 and its transmissions into communities in Vietnam. Methods and Material: We accessed the database of COVID-19 by the Ministry of Health, Vietnam. Variables included sources of infection, age, sex, nationality, the dates of onset of symptoms and discharge from hospitals, and ID of each patient tested positive with COVID-19. Information from each patient was linked to the sources of infection to identify workplace-related clusters. Among 314 patients, we excluded 43 cases related to two charter flights, the remaining 271 cases were eligible for the study.Results: The biggest cluster of hospital canteen included 26 workers and their 31 family members or hospital’s patients. The second biggest cluster included a pilot of the Vietnam airlines and other 16 patients who have close contact with him at the Bar Buddha at Ho Chi Minh City. A total of 87 patients (32.1% of 271 cases) were related to these workplace-related clusters. The suspected time and the clinical course was significantly longer in the workplace-related clusters than other patients (mean 6.52 vs. 4.05 days, p=0.0191) and (mean 28.71 vs. 20.52 days, p=0.0005), respectively. Conclusions: Because COVID-19 infection at workplaces was responsible for nearly one-third of the total patients, there was a novel emerged occupational risk factor at work due to coronavirus infection. Safety at the workplace in preventing COVID-19 transmission is highly needed.
Objectives: The aim was to describe the characteristics and outcomes of treatments for coronavirus infection in cancer survivors in Viet Nam from 23 January to 6 May 2020. Methods: We accessed data registration and publication of cases tested positive with COVID-19 by the Ministry of Health in Viet Nam. Characteristics of reported positive cases included age, sex, sources of infection, nationality, the onset of symptoms, and history of chronic diseases. The outcomes included incubation, suspected, clinical course, and clearance time by the subgroup of patients having a history of cancer and non-cancer. T-test was used to compare two means of these groups. Results: Three men patients were cancer survivors (1.1% of 271 cases),a Chinese business aged 66 having lung cancer (ICD-10: C34), a Sweden tourism aged 64 having blood cancer (ICD-10: C81-C96), and a Vietnamese aged 71 having liver cancer (ICD-10: C22). The remaining 268 patients were free-cancer. The clinical course of three cancer survivors was 17.3 days that were shorter 3.2 days when compared to non-cancer, p=0.2068. The estimated suspected time was longer in cancer survivors (5.3 days) than non-cancer (1.5 days), p =0.0394. The mean age was older in cancer survivors (67-year-old) than non-cancer (35.5-year-old), p =0.0003. Conclusions: Cancer survivors might be at high risk of COVID-19 infection due to their underlying vulnerable health condition related to cancer disease and they need extra care to minimize the risk of infection from coronavirus.
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