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This paper proposes a smart system of virus detection that can classify a file as benign or malware with high accuracy detection rate. The approach is based on the aspects of the artificial immune system, in which an artificial immune network is used as a pool to create and develop virus detectors that can detect unknown data. Besides, a deep learning model is also used as the main classifier because of its advantages in binary classification problems. This method can achieve a detection rate of 99.08% on average, with a very low false positive rate.

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