Introduction. Cone-beam computed tomography (CBCT) is considered to be the most informative radiographic method for pre- and postoperative analysis of the maxillary anatomy and for avoiding further complication. Canalis sinuosus is one of such structures that damage can go along with bleeding and neurological symptomatology. The aim of the study was to investigate radiological and morphometric features of the canalis sinuosus in Russian population using CBCT technique. Materials and Methods. 150 CBCT scans of 61 males and 89 females aged from 24 to 80 years were retrospectively studied with different slice thickness and evaluated with regards to prevalence and diameter among age and gender groups in Russia. Results. CS prevalence in this study was 67%, and CS was most frequently presented in the lateral incisor region (33.5%). Women showed statistically higher CS prevalence (p<0.01) than the male group, and there was no statistically significant difference observed between occurrence and localization of CS and age groups. Conclusion. CBCT examination demonstrated good diagnostic efficiency in CS visualization, and the CS may have variations on its location and prevalence with statistically significant differences between the gender group and without significant differences among age groups and can depend on the population.

Background: Mucositis is a common and severe complication of anti-tumour therapy. The use of plant-derived drugs in patients with malignant neoplasms of the oral mucosa and maxillofacial area according to a certain group of dental risks shows good results and can be considered as one of the promising methods for the prevention and treatment of mucositis. One of the methods confirming the effectiveness of the local treatment is the determination of hemomicrocirculation in the tissues of the oral mucosa. Objectives: To determine the state of hemomicrocirculation in the tissues of oral mucosa in patients with oropharyngeal squamous cell carcinoma at different stages of anti-tumour therapy, as well as during the application of different methods for local treatment of oral mucositis. Materials and Methods: From January 2017 to May 2018, in the Department of Radiotherapy of the National Medical Research Radiological Centre (NMRRC) of the Russian Federation, the microcirculatory parameter (MP) of hemomicrocirculation was determined in 69 patients diagnosed with oropharyngeal squamous cell carcinoma. Results: In group I, hemomicrocirculation was higher at all measurement points than in group II. Clinical manifestations of oral mucositis in group I develop later than in group II and correspond to the maximum value of hemomicrocirculation in each group. Conclusions: The results confirm that the use of longacting plant-derived drugs is more effective than traditional oral irrigation with chamomile decoction and oleotherapy for the prevention and treatment of oral mucositis: Decrease in microcirculation indicators of group I (using the drugs) is 7.4% less than one of group II (not using the drugs); p <0.04. K E Y w O R D S-mucositis, hemomicrocirculation, longacting plant-derived drugs.